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SGOL1 shugoshin-like 1 (S. pombe) [ Homo sapiens (human) ]

Gene ID: 151648, updated on 5-Apr-2015
Official Symbol
SGOL1provided by HGNC
Official Full Name
shugoshin-like 1 (S. pombe)provided by HGNC
Primary source
HGNC:HGNC:25088
See related
Ensembl:ENSG00000129810; HPRD:12377; MIM:609168; Vega:OTTHUMG00000130479
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGO; CAID; Sgo1; NY-BR-85
Summary
The protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis-segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found along the length of the chromosome arms during mitotic prophase. An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID:18331714). Mutations in this gene have been associated with Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome, characterized by the co-occurrence of Sick Sinus Syndrome (SSS) and Chronic Intestinal Pseudo-obstruction (CIPO) within the first four decades of life (PMID:25282101). Fibroblast cells from CAID patients exhibited both increased cell proliferation and higher rates of senescence. Pseudogenes of this gene have been found on chromosomes 1 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Orthologs
See SGOL1 in MapViewer
Location:
3p24.3
Exon count:
13
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (20159046..20188131, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (20202085..20227724, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2C-like domain containing 1 Neighboring gene ribosomal protein L39 pseudogene 18 Neighboring gene K(lysine) acetyltransferase 2B Neighboring gene microRNA 3135a Neighboring gene SGOL1 antisense RNA 1 Neighboring gene RNA, Ro-associated Y4 pseudogene 22 Neighboring gene uncharacterized LOC101927829

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Chronic atrial and intestinal dysrhythmia
MedGen: CN225197 OMIM: 616201 GeneReviews: Not available
not available

NHGRI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
NHGRI GWA Catalog
Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr interferes with the heterochromatin structure by displacing HP1-alpha and HP1-gamma proteins in interphase, which leads to relocalization of the centromere chromatin proteins Mis12, Sgo1, and CPC after prophase PubMed
vpr HIV-1 Vpr inhibits Sgo1 expression in spread chromosomes and prometaphase cells PubMed

Go to the HIV-1, Human Interaction Database

  • Aurora B signaling, organism-specific biosystem (from Pathway Interaction Database)
    Aurora B signaling, organism-specific biosystem
    Aurora B signaling
  • Cell Cycle, organism-specific biosystem (from REACTOME)
    Cell Cycle, organism-specific biosystem
    Cell Cycle
  • Cell Cycle, Mitotic, organism-specific biosystem (from REACTOME)
    Cell Cycle, Mitotic, organism-specific biosystemThe replication of the genome and the subsequent segregation of chromosomes into daughter cells are controlled by a series of events collectively known as the cell cycle. DNA replication is carried o...
  • M Phase, organism-specific biosystem (from REACTOME)
    M Phase, organism-specific biosystemMitosis, or the M phase, involves nuclear division and cytokinesis, where two identical daughter cells are produced. Mitosis involves prophase, prometaphase, metaphase, anaphase, and telophase. Fin...
  • Mitotic Anaphase, organism-specific biosystem (from REACTOME)
    Mitotic Anaphase, organism-specific biosystemIn anaphase, the paired chromosomes separate at the centromeres, and move to the opposite sides of the cell. The movement of the chromosomes is facilitated by a combination of kinetochore movement al...
  • Mitotic Metaphase and Anaphase, organism-specific biosystem (from REACTOME)
    Mitotic Metaphase and Anaphase, organism-specific biosystemMetaphase is marked by the formation of the metaphase plate. The metaphase plate is formed when the spindle fibers align the chromosomes along the middle of the cell. Such an organization helps to ...
  • Mitotic Prometaphase, organism-specific biosystem (from REACTOME)
    Mitotic Prometaphase, organism-specific biosystemThe dissolution of the nuclear membrane marks the beginning of the prometaphase. Kinetochores are created when proteins attach to the centromeres. Microtubules then attach at the kinetochores, and th...
  • Oocyte meiosis, organism-specific biosystem (from KEGG)
    Oocyte meiosis, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
  • Oocyte meiosis, conserved biosystem (from KEGG)
    Oocyte meiosis, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, homologous chromosomes recombine and then segrega...
  • PLK1 signaling events, organism-specific biosystem (from Pathway Interaction Database)
    PLK1 signaling events, organism-specific biosystem
    PLK1 signaling events
  • RHO GTPase Effectors, organism-specific biosystem (from REACTOME)
    RHO GTPase Effectors, organism-specific biosystemRHO GTPases regulate cell behaviour by activating a number of downstream effectors that regulate cytoskeletal organization, intracellular trafficking and transcription (reviewed by Sahai and Marshall...
  • RHO GTPases Activate Formins, organism-specific biosystem (from REACTOME)
    RHO GTPases Activate Formins, organism-specific biosystemFormins are a family of proteins with 15 members in mammals, organized into 8 subfamilies. Formins are involved in the regulation of actin cytoskeleton. Many but not all formin family members are act...
  • Resolution of Sister Chromatid Cohesion, organism-specific biosystem (from REACTOME)
    Resolution of Sister Chromatid Cohesion, organism-specific biosystemThe resolution of sister chromatids in mitotic prometaphase involves removal of cohesin complexes from chromosomal arms, with preservation of cohesion at centromeres (Losada et al. 1998, Hauf et al. ...
  • Separation of Sister Chromatids, organism-specific biosystem (from REACTOME)
    Separation of Sister Chromatids, organism-specific biosystemWhile sister chromatids resolve in prometaphase, separating along chromosomal arms, the cohesion of sister centromeres persists until anaphase. At the anaphase onset, the anaphase promoting complex/c...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signaling by Rho GTPases, organism-specific biosystem (from REACTOME)
    Signaling by Rho GTPases, organism-specific biosystemThe Rho family of small guanine nucleotide binding proteins is one of five generally recognized branches of the Ras superfamily. Like most Ras superfamily members, typical Rho proteins function as bi...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ14230

Gene Ontology Provided by GOA

Function Evidence Code Pubs
kinase binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
attachment of spindle microtubules to kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
cell division IEA
Inferred from Electronic Annotation
more info
 
centriole-centriole cohesion IDA
Inferred from Direct Assay
more info
PubMed 
centriole-centriole cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromosome segregation IDA
Inferred from Direct Assay
more info
PubMed 
meiotic chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic cell cycle TAS
Traceable Author Statement
more info
 
mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
small GTPase mediated signal transduction TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
condensed chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
condensed nuclear chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
mitotic cohesin complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
spindle pole IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
shugoshin-like 1
Names
shugoshin-like 1
serologically defined breast cancer antigen NY-BR-85
shugoshin 1AB protein
shugoshin 1CD protein
shugoshin 1EF protein
shugoshin 1GH protein
shugoshin 1KL protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_042062.1 RefSeqGene

    Range
    4999..30639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001012409.3NP_001012409.1  shugoshin-like 1 isoform 1

    See identical proteins and their annotated locations for NP_001012409.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (A1) differs in the 5' UTR compared to variant 1. Both variants 1 and A1 encode the same isoform (1).
    Source sequence(s)
    AB187577, AB193058, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46773.1
    UniProtKB/TrEMBL
    B5BUA4
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  2. NM_001012410.4NP_001012410.1  shugoshin-like 1 isoform EF

    See identical proteins and their annotated locations for NP_001012410.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1F, PMID:15737064; also known as A2) differs in the 5' UTR and contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1EF which is longer and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1E and Sgo1F encode the same isoform (1EF).
    Source sequence(s)
    AB187578, AB193061, BX494477
    Consensus CDS
    CCDS33716.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Related
    ENSP00000263753, OTTHUMP00000208169, ENST00000263753, OTTHUMT00000340498
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  3. NM_001012411.3NP_001012411.1  shugoshin-like 1 isoform 1CD

    See identical proteins and their annotated locations for NP_001012411.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1C, PMID:15737064; also known as B1) differs in its 5' UTR and uses an alternate in-frame splice site in its central coding region compared to variant 1. It encodes isoform 1CD which is shorter and has a distinct internal amino acid, compared to isoform 1. Both variants Sgo1C and Sgo1D encode the same isoform (1CD).
    Source sequence(s)
    AB193058, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46774.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:219244
    Shugoshin_C; Shugoshin C terminus
  4. NM_001012412.4NP_001012412.1  shugoshin-like 1 isoform 1GH

    See identical proteins and their annotated locations for NP_001012412.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1H, PMID:15737064, also known as B2) differs in its 5' UTR, uses an alternate in-frame splice site in its central coding region, and contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1GH which is shorter, has a distinct internal amino acid, and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1G and Sgo1H encode the same isoform (1GH).
    Source sequence(s)
    AB187578, AB193063, BX494477
    Consensus CDS
    CCDS46771.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Related
    ENSP00000394625, OTTHUMP00000208165, ENST00000419233, OTTHUMT00000340494
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:219244
    Shugoshin_C; Shugoshin C terminus
  5. NM_001012413.3NP_001012413.1  shugoshin-like 1 isoform 1AB

    See identical proteins and their annotated locations for NP_001012413.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1B, PMID:15737064; also known as C1) differs in its 5' UTR and lacks an alternate in-frame exon in its central coding region compared to variant 1. It encodes isoform 1AB which is shorter and has a distinct internal amino acid, compared to isoform 1. Both variants Sgo1A and Sgo1B encode the same isoform (1AB).
    Source sequence(s)
    AB193057, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46772.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:202227
    Shugoshin_C; Shugoshin C terminus
  6. NM_001199251.2NP_001186180.1  shugoshin-like 1 isoform 1

    See identical proteins and their annotated locations for NP_001186180.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and A1 encode the same isoform (1).
    Source sequence(s)
    AB190994, AC099057, AF308299, AK308095, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46773.1
    UniProtKB/TrEMBL
    B5BUA4
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  7. NM_001199252.2NP_001186181.1  shugoshin-like 1 isoform EF

    See identical proteins and their annotated locations for NP_001186181.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1E, PMID:15737064) contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1EF which is longer and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1E and Sgo1F encode the same isoform (1EF).
    Source sequence(s)
    AB187578, AB193060, BX494477
    Consensus CDS
    CCDS33716.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  8. NM_001199253.2NP_001186182.1  shugoshin-like 1 isoform 1CD

    See identical proteins and their annotated locations for NP_001186182.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1D, PMID:15737064) uses an alternate in-frame splice site in its central coding region compared to variant 1. It encodes isoform 1CD which is shorter and has a distinct internal amino acid, compared to isoform 1. Both variants Sgo1C and Sgo1D encode the same isoform (1CD).
    Source sequence(s)
    AB193059, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46774.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:219244
    Shugoshin_C; Shugoshin C terminus
  9. NM_001199254.2NP_001186183.1  shugoshin-like 1 isoform 1GH

    See identical proteins and their annotated locations for NP_001186183.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1G, PMID:15737064) uses an alternate in-frame splice site in its central coding region and contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1GH which is shorter, has a distinct internal amino acid, and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1G and Sgo1H encode the same isoform (1GH).
    Source sequence(s)
    AB187578, AB193062, BX494477
    Consensus CDS
    CCDS46771.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:219244
    Shugoshin_C; Shugoshin C terminus
  10. NM_001199255.2NP_001186184.1  shugoshin-like 1 isoform 1AB

    See identical proteins and their annotated locations for NP_001186184.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1A, PMID:15737064) lacks an alternate in-frame exon in its central coding region compared to variant 1. It encodes isoform 1AB which is shorter and has a distinct internal amino acid, compared to isoform 1. Both variants Sgo1A and Sgo1B encode the same isoform (1AB).
    Source sequence(s)
    AB193056, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
    Consensus CDS
    CCDS46772.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:202227
    Shugoshin_C; Shugoshin C terminus
  11. NM_001199256.2NP_001186185.1  shugoshin-like 1 isoform 1KL

    See identical proteins and their annotated locations for NP_001186185.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1K, PMID:15737064; also known as sSGO1, PMID:18331714) lacks an alternate in-frame exon in its central coding region, and contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1KL which is shorter, has a distinct internal amino acid, and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1K and Sgo1L encode the same isoform (1KL).
    Source sequence(s)
    AB187578, AB193065, BX494477
    Consensus CDS
    CCDS2635.1
    UniProtKB/TrEMBL
    A0A024R2J4
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:202227
    Shugoshin_C; Shugoshin C terminus
  12. NM_001199257.2NP_001186186.1  shugoshin-like 1 isoform 1J

    See identical proteins and their annotated locations for NP_001186186.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1J, PMID:15737064) uses an alternate splice site in its 3' coding region, lacks two exons in the 3' coding region, and contains an alternate 3' terminal exon compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1J which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AB187578, AB193064, BX494477
    Consensus CDS
    CCDS56243.1
    UniProtKB/Swiss-Prot
    Q5FBB7
    Conserved Domains (1) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
  13. NM_138484.4NP_612493.1  shugoshin-like 1 isoform 1KL

    See identical proteins and their annotated locations for NP_612493.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (Sgo1L, PMID:15737064; also known as sSGO1, PMID:18331714 or C2) differs in the 5' UTR, lacks an alternate in-frame exon in its central coding region, and contains an alternate 3' terminal segment compared to variant 1, resulting in a novel 3' coding region and distinct 3' UTR. It encodes isoform 1KL which is shorter, has a distinct internal amino acid, and has a distinct C-terminus, compared to isoform 1. Both variants Sgo1K and Sgo1L encode the same isoform (1KL).
    Source sequence(s)
    AB187578, AB193066, BX494477
    Consensus CDS
    CCDS2635.1
    UniProtKB/TrEMBL
    A0A024R2J4
    UniProtKB/Swiss-Prot
    Q5FBB7
    Related
    ENSP00000306581, OTTHUMP00000161045, ENST00000306698, OTTHUMT00000252878
    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:202227
    Shugoshin_C; Shugoshin C terminus

RNA

  1. NR_131179.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14) differs in its 5' terminal exon and lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB193058, AB567657, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516
  2. NR_131180.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15) differs in its 5' terminal exon and lacks two alternate internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB193058, AB567656, AC099057, AF308299, BC032696, BM144963, BX494477, BX648516

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

    Range
    20159046..20188131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011533377.1XP_011531679.1  

    See identical proteins and their annotated locations for XP_011531679.1

    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  2. XM_011533373.1XP_011531675.1  

    See identical proteins and their annotated locations for XP_011531675.1

    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  3. XM_011533376.1XP_011531678.1  

    See identical proteins and their annotated locations for XP_011531678.1

    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  4. XM_011533374.1XP_011531676.1  

    See identical proteins and their annotated locations for XP_011531676.1

    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus
  5. XM_011533375.1XP_011531677.1  

    See identical proteins and their annotated locations for XP_011531677.1

    Conserved Domains (2) summary
    pfam07558
    Location:2267
    Shugoshin_N; Shugoshin N-terminal coiled-coil region
    pfam07557
    Location:471496
    Shugoshin_C; Shugoshin C terminus

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 Alternate CHM1_1.1

    Range
    20153920..20179582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)