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HORMAD2 HORMA domain containing 2 [ Homo sapiens (human) ]

Gene ID: 150280, updated on 7-May-2016
Official Symbol
HORMAD2provided by HGNC
Official Full Name
HORMA domain containing 2provided by HGNC
Primary source
HGNC:HGNC:28383
See related
Ensembl:ENSG00000176635 HPRD:13668; Vega:OTTHUMG00000150881
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT46.2
Orthologs
Location:
22q12.2
Exon count:
16
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 22 NC_000022.11 (30080069..30210882)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (30476453..30573064)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene myotubularin related protein 3 Neighboring gene HORMAD2 antisense RNA 1 Neighboring gene microRNA 6818 Neighboring gene calponin 2 pseudogene 1 Neighboring gene ribosomal protein L36 pseudogene 17 Neighboring gene ribosomal protein S3a pseudogene 51 Neighboring gene uncharacterized LOC105372988 Neighboring gene leukemia inhibitory factor Neighboring gene oncostatin M

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Common variants at five new loci associated with early-onset inflammatory bowel disease.
NHGRI GWA Catalog
Genome-wide association study identifies susceptibility loci for IgA nephropathy.
NHGRI GWA Catalog
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
integrase gag-pol Analysis of HIV-1 proviral integration sites in antiretroviral treatment patients indicates that HORMAD2 gene favors HIV-1 integration for expansion and persistence of infected cells, suggesting HIV-1 IN interacts with HORMAD2 PubMed

Go to the HIV-1, Human Interaction Database

Markers

Homology

Clone Names

  • MGC26710

Gene Ontology Provided by GOA

Process Evidence Code Pubs
meiotic nuclear division ISS
Inferred from Sequence or Structural Similarity
more info
 
meiotic sister chromatid cohesion ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
chromosome ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
synaptonemal complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
HORMA domain-containing protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152510.2NP_689723.1  HORMA domain-containing protein 2

    See identical proteins and their annotated locations for NP_689723.1

    Status: PROVISIONAL

    Source sequence(s)
    BC030013
    Consensus CDS
    CCDS46683.1
    UniProtKB/Swiss-Prot
    Q8N7B1
    Related
    ENSP00000336984, OTTHUMP00000198645, ENST00000336726, OTTHUMT00000320416
    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p2 Primary Assembly

    Range
    30080069..30210882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529919.1XP_011528221.1  

    Conserved Domains (1) summary
    pfam02301
    Location:11140
    HORMA; HORMA domain
  2. XM_011529913.1XP_011528215.1  

    See identical proteins and their annotated locations for XP_011528215.1

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  3. XM_011529914.1XP_011528216.1  

    See identical proteins and their annotated locations for XP_011528216.1

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  4. XM_011529918.1XP_011528220.1  

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  5. XM_006724147.2XP_006724210.2  

    See identical proteins and their annotated locations for XP_006724210.2

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  6. XM_011529916.1XP_011528218.1  

    See identical proteins and their annotated locations for XP_011528218.1

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  7. XM_011529915.1XP_011528217.1  

    See identical proteins and their annotated locations for XP_011528217.1

    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain
  8. XM_011529917.1XP_011528219.1  

    See identical proteins and their annotated locations for XP_011528219.1

    UniProtKB/Swiss-Prot
    Q8N7B1
    Related
    ENSP00000385055, OTTHUMP00000198644, ENST00000403975, OTTHUMT00000320415
    Conserved Domains (1) summary
    pfam02301
    Location:27228
    HORMA; HORMA domain

Alternate CHM1_1.1

Genomic

  1. NC_018933.2 Alternate CHM1_1.1

    Range
    30435626..30532240
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)