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Gk glycerol kinase [ Mus musculus (house mouse) ]

Gene ID: 14933, updated on 8-May-2016
Official Symbol
Gkprovided by MGI
Official Full Name
glycerol kinaseprovided by MGI
Primary source
MGI:MGI:106594
See related
Ensembl:ENSMUSG00000025059 Vega:OTTMUSG00000017916
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gyk; D930012N15Rik
Orthologs
Location:
X 39.32 cM; X C-D
Exon count:
22
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (85701937..85776819, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (82947276..83022158, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene ferritin, heavy polypeptide-like 17, member A Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 3 Neighboring gene predicted gene, 39523 Neighboring gene RIKEN cDNA 5430427O19 gene Neighboring gene replication protein A 14 kDa subunit pseudogene Neighboring gene mitochondrial import receptor subunit TOM20 homolog pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
glycerol kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
glycerol kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
histone binding ISO
Inferred from Sequence Orthology
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glucose homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycerol metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycerol-3-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
glycerol-3-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
triglyceride metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
glycerol kinase
Names
ATP:glycerol 3-phosphotransferase
glycerokinase
NP_001281067.1
NP_001281069.1
NP_032220.1
NP_997609.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001294138.1NP_001281067.1  glycerol kinase isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains one alternate exon and lacks two alternate exons in the coding region, but maintains the reading frame, compared to variant 4. The encoded isoform (3) is shorter than isoform 4.
    Source sequence(s)
    AK169424, AK169525, AL645567, BQ176629
    Consensus CDS
    CCDS81150.1
    UniProtKB/TrEMBL
    B1ASZ3, Q3TEN9, Q3TET2
    Related
    ENSMUSP00000120754, OTTMUSP00000019467, ENSMUST00000142152, OTTMUST00000043305
    Conserved Domains (2) summary
    cd07792
    Location:11541
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11541
    glycerol_kin; glycerol kinase
  2. NM_001294140.1NP_001281069.1  glycerol kinase isoform 4

    See identical proteins and their annotated locations for NP_001281069.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (4).
    Source sequence(s)
    AK044308, AK169424, AK169525, AL645567, AL672056, BQ176629
    Consensus CDS
    CCDS81149.1
    UniProtKB/Swiss-Prot
    Q64516
    UniProtKB/TrEMBL
    Q3TEN9, Q3TET2
    Related
    ENSMUSP00000109611, OTTMUSP00000019465, ENSMUST00000113978, OTTMUST00000043303
    Conserved Domains (2) summary
    cd07792
    Location:11519
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11519
    glycerol_kin; glycerol kinase
  3. NM_008194.3NP_032220.1  glycerol kinase isoform 1

    See identical proteins and their annotated locations for NP_032220.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks two alternate in-frame exons in the coding region compared to variant 4. The encoded isoform (1) is shorter than isoform 4.
    Source sequence(s)
    AK169424, AK169525, AL672056, BQ176629
    Consensus CDS
    CCDS53126.1
    UniProtKB/Swiss-Prot
    Q64516
    UniProtKB/TrEMBL
    Q3TEN9, Q3TET2
    Related
    ENSMUSP00000026039, OTTMUSP00000019464, ENSMUST00000026039, OTTMUST00000043302
    Conserved Domains (2) summary
    cd07792
    Location:11513
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11513
    glycerol_kin; glycerol kinase
  4. NM_212444.2NP_997609.1  glycerol kinase isoform 2

    See identical proteins and their annotated locations for NP_997609.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region compared to variant 4. The encoded isoform (2) is shorter than isoform 4.
    Source sequence(s)
    AL645567, AL672056
    Consensus CDS
    CCDS41050.1
    UniProtKB/Swiss-Prot
    Q64516
    Related
    ENSMUSP00000119564, OTTMUSP00000019466, ENSMUST00000156390, OTTMUST00000043304
    Conserved Domains (2) summary
    cd07792
    Location:11513
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11513
    glycerol_kin; glycerol kinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    85701937..85776819 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527831.2XP_006527894.1  

    Conserved Domains (2) summary
    cd07792
    Location:11541
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11541
    glycerol_kin; glycerol kinase
  2. XM_006527833.2XP_006527896.1  

    Conserved Domains (2) summary
    cd07792
    Location:11547
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11547
    glycerol_kin; glycerol kinase
  3. XM_006527829.2XP_006527892.1  

    Conserved Domains (2) summary
    cd07792
    Location:11547
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11547
    glycerol_kin; glycerol kinase

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    76897628..76973181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)