Display Settings:


Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

E6 transforming protein [ Human papillomavirus type 16 ]

Gene ID: 1489078, updated on 6-Apr-2014
Gene symbol
Gene description
transforming protein
Locus tag
Gene type
protein coding
RefSeq status
Human papillomavirus type 16
Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Alphapapillomavirus
Sequence :
NC_001526.2 (83..559)

NC_001526.2Genomic Context describing neighboring genes Neighboring gene transforming protein Neighboring gene E1 Neighboring gene regulatory protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Apoptosis, organism-specific biosystem (from REACTOME)
    Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...
  • Death Receptor Signalling, organism-specific biosystem (from REACTOME)
    Death Receptor Signalling, organism-specific biosystemThe death receptors, all cell-surface receptors, begin the process of caspase activation. The common feature of these type 1 transmembrane proteins is the "death-domain" a conserved cytoplasmic motif...
  • Extrinsic Pathway for Apoptosis, organism-specific biosystem (from REACTOME)
    Extrinsic Pathway for Apoptosis, organism-specific biosystemKnown as the "death receptor pathway" the extrinsic or caspase 8/10 dependent pathway is activated by ligand binding. The "death receptors" are specialized cell-surface receptors including Fas/CD95, ...
  • FasL/ CD95L signaling, organism-specific biosystem (from REACTOME)
    FasL/ CD95L signaling, organism-specific biosystemThe Fas family of cell surface receptors initiate the apototic pathway through interaction with the external ligand, FasL. The cytoplasmic domain of Fas interacts with a number of molecules in the t...
  • Regulation of Telomerase, organism-specific biosystem (from Pathway Interaction Database)
    Regulation of Telomerase, organism-specific biosystem
    Regulation of Telomerase
  • TNF signaling, organism-specific biosystem (from REACTOME)
    TNF signaling, organism-specific biosystemThe Tumor Necrosis Factor alpha (TNF-alpha) mediated apoptosis pathway has been implicated in the pathogenesis of a number of diseases including sepsis, diabetes, cancer, osteoporosis, multiple scler...
  • TRAIL signaling, organism-specific biosystem (from REACTOME)
    TRAIL signaling, organism-specific biosystemTumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand (TRAIL/Apo2L) is a member of the tumor necrosis factor (TNF) family. This group of apoptosis induction pathways all work throug...
Products Interactant Other Gene Complex Source Pubs Description
transforming protein
  • E6 ORF from 65 to 559; putative

VOG classification


  • VOGd0194 [R] Early oncoprotein E6
  • Regulation of Cellular Metabolism

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly


  1. NC_001526.2

    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_041325.1 transforming protein [Human papillomavirus type 16]

    See proteins identical to NP_041325.1


    Conserved Domains (1) summary
    Blast Score: 406
    E6; Early Protein (E6)

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...