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E6 transforming protein [ Human papillomavirus type 16 ]

Gene ID: 1489078, updated on 6-Apr-2014
Gene symbol
E6
Gene description
transforming protein
Locus tag
HpV16gp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Human papillomavirus type 16
Lineage
Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Alphapapillomavirus
Sequence :
NC_001526.2 (83..559)

NC_001526.2Genomic Context describing neighboring genes Neighboring gene transforming protein Neighboring gene E1 Neighboring gene regulatory protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Apoptosis, organism-specific biosystem (from REACTOME)
    Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...
  • Death Receptor Signalling, organism-specific biosystem (from REACTOME)
    Death Receptor Signalling, organism-specific biosystemThe death receptors, all cell-surface receptors, begin the process of caspase activation. The common feature of these type 1 transmembrane proteins is the "death-domain" a conserved cytoplasmic motif...
  • Extrinsic Pathway for Apoptosis, organism-specific biosystem (from REACTOME)
    Extrinsic Pathway for Apoptosis, organism-specific biosystemKnown as the "death receptor pathway" the extrinsic or caspase 8/10 dependent pathway is activated by ligand binding. The "death receptors" are specialized cell-surface receptors including Fas/CD95, ...
  • FasL/ CD95L signaling, organism-specific biosystem (from REACTOME)
    FasL/ CD95L signaling, organism-specific biosystemThe Fas family of cell surface receptors initiate the apototic pathway through interaction with the external ligand, FasL. The cytoplasmic domain of Fas interacts with a number of molecules in the t...
  • Regulation of Telomerase, organism-specific biosystem (from Pathway Interaction Database)
    Regulation of Telomerase, organism-specific biosystem
    Regulation of Telomerase
  • TNF signaling, organism-specific biosystem (from REACTOME)
    TNF signaling, organism-specific biosystemThe Tumor Necrosis Factor alpha (TNF-alpha) mediated apoptosis pathway has been implicated in the pathogenesis of a number of diseases including sepsis, diabetes, cancer, osteoporosis, multiple scler...
  • TRAIL signaling, organism-specific biosystem (from REACTOME)
    TRAIL signaling, organism-specific biosystemTumor necrosis factor-related apoptosis-inducing ligand or Apo 2 ligand (TRAIL/Apo2L) is a member of the tumor necrosis factor (TNF) family. This group of apoptosis induction pathways all work throug...
Products Interactant Other Gene Complex Source Pubs Description
Names
transforming protein
NP_041325.1
  • E6 ORF from 65 to 559; putative

VOG classification

Description:

  • VOGd0194 [R] Early oncoprotein E6
  • Regulation of Cellular Metabolism

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001526.2

    Range
    83..559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_041325.1 transforming protein [Human papillomavirus type 16]

    See proteins identical to NP_041325.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03126
    UniProtKB/TrEMBL
    Q547J2
    Conserved Domains (1) summary
    pfam00518
    Location:37146
    Blast Score: 406
    E6; Early Protein (E6)

Supplemental Content

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