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    Gstt2 glutathione S-transferase, theta 2 [ Mus musculus (house mouse) ]

    Gene ID: 14872, updated on 11-May-2013
    Official Symbol
    Gstt2provided by MGI
    Official Full Name
    glutathione S-transferase, theta 2provided by MGI
    Primary source
    MGI:106188
    See related
    Ensembl:ENSMUSG00000033318
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Yrs; mGSTT2; AI266894
    Location :
    10 B5-C1; 10 38.58 cM
    Sequence :
    Chromosome: 10; NC_000076.6 (75831845..75834881, complement)
    See Gstt2 in Epigenomics, MapViewer

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase, theta 1 Neighboring gene glutathione S-transferase, theta 4 Neighboring gene macrophage migration inhibitory factor Neighboring gene Der1-like domain family, member 3

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Kamileri I, et al. Proc Natl Acad Sci U S A, 2012 Feb 21. PMID 22323595.
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    4. A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Endoh-Yamagami S, et al. Dev Biol, 2010 Apr 1. PMID 20096683.
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693.

    See all (22) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    glutathione transferase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    glutathione metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    Preferred Names
    glutathione S-transferase theta-2
    Names
    glutathione S-transferase theta-2
    GST class-theta-2
    NP_034491.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010361.2 → NP_034491.2  glutathione S-transferase theta-2

      Status: VALIDATED

      Source sequence(s)
      AK158939, BU938629
      Consensus CDS
      CCDS48601.1
      UniProtKB/Swiss-Prot
      Q61133
      Related
      ENSMUSP00000046324, ENSMUST00000038257
      Conserved Domains (3) summary
      COG0625
      Location:3 – 210
      Blast Score: 223
      Gst; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      cd03050
      Location:3 – 78
      Blast Score: 285
      GST_N_Theta; GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with ...
      cd03183
      Location:91 – 216
      Blast Score: 410
      GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p1 C57BL/6J

      Range
      75831845..75834881, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000032.1 Alternate Mm_Celera

      Range
      76876522..76879558, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01086815.1 (146948..149984) None
    genomic AC007961.32 (120763..123164) None 129S6/SvEvTac
    genomic AC142499.9 (89933..92334) None C57BL/6J
    genomic CH466553.2 EDL31881.1 mixed
      EDL31882.1 mixed
    genomic U48419.1 AAB03533.1 129/Sv
    mRNA AK002392.1 BAB22065.1 C57BL/6J
    mRNA AK079739.1 None C57BL/6J
    mRNA AK158939.1 BAE34734.1 C57BL/6J
    mRNA BC012707.1 AAH12707.1 CZECHII
    mRNA BU938629.1 None
    mRNA U48420.1 AAB03534.1 C57BL/6 x CBA
    mRNA X98056.1 CAA66666.1 B6C3F1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q61133.4 GenPept UniProtKB/Swiss-Prot:Q61133

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • EST
        Link to related EST entry
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

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