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Gstt1 glutathione S-transferase, theta 1 [ Mus musculus (house mouse) ]

Gene ID: 14871, updated on 8-May-2016
Official Symbol
Gstt1provided by MGI
Official Full Name
glutathione S-transferase, theta 1provided by MGI
Primary source
MGI:MGI:107379
See related
Ensembl:ENSMUSG00000001663 Vega:OTTMUSG00000026319
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gstt1-1; AI255817
Orthologs
Location:
10 38.58 cM; 10 B5-C1
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (75783813..75798584, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (75246558..75261329, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene D-dopachrome tautomerase Neighboring gene glutathione S-transferase, theta 3 Neighboring gene glutathione S-transferase, theta 4 Neighboring gene glutathione S-transferase, theta 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alkylhalidase activity ISO
Inferred from Sequence Orthology
more info
 
glutathione peroxidase activity ISO
Inferred from Sequence Orthology
more info
 
glutathione transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
glutathione transferase activity ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA modification ISO
Inferred from Sequence Orthology
more info
 
cellular oxidant detoxification ISO
Inferred from Sequence Orthology
more info
 
dichloromethane metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutathione metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glutathione metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutathione metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
glutathione S-transferase theta-1
Names
GST class-theta-1
NP_032211.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008185.3NP_032211.3  glutathione S-transferase theta-1

    See identical proteins and their annotated locations for NP_032211.3

    Status: VALIDATED

    Source sequence(s)
    AI255817, AK002338, BY015234, W54467
    Consensus CDS
    CCDS23932.1
    UniProtKB/Swiss-Prot
    Q64471
    UniProtKB/TrEMBL
    Q9DCY6
    Related
    ENSMUSP00000001713, OTTMUSP00000032399, ENSMUST00000001713, OTTMUST00000065097
    Conserved Domains (3) summary
    cd03183
    Location:91217
    GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
    COG0625
    Location:3212
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03050
    Location:378
    GST_N_Theta; GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    75783813..75798584 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513239.2XP_006513302.2  

    Conserved Domains (3) summary
    cd03183
    Location:87213
    GST_C_Theta; C-terminal, alpha helical domain of Class Theta Glutathione S-transferases
    COG0625
    Location:1208
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cl00388
    Location:3474
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    76828580..76843364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)