HIPK4 homeodomain interacting protein kinase 4 [Homo sapiens] - Gene

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Summary

Official Symbol: HIPK4provided by HGNC
Official Full Name: homeodomain interacting protein kinase 4provided by HGNC
Primary source: HGNC:19007
See related: Ensembl:ENSG00000160396; HPRD:13652; MIM:611712
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: FLJ32818

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Genomic context

Location :: 19q13.2

Sequence :: Chromosome: 19; NC_000019.9 (40885178..40896094, complement)

See HIPK4 in Epigenomics, MapViewer

Chromosome 19 - NC_000019.9 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

homeodomain interacting protein kinase 4 could phosphorylate human p53 protein at serine 9, both in vitro and in vivo
Title: Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9.

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

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Function	Evidence Code	Pubs
ATP binding	IEA Inferred from Electronic Annotation more info
nucleotide binding	IEA Inferred from Electronic Annotation more info
protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: homeodomain-interacting protein kinase 4

Names: homeodomain-interacting protein kinase 4

NP_653286.2

EC 2.7.11.1

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_144685.3 → NP_653286.2 homeodomain-interacting protein kinase 4

Status: PROVISIONAL

Source sequence(s)

BC034501

Consensus CDS

CCDS12555.1

UniProtKB/Swiss-Prot

Q8NE63

Related

ENSP00000291823, ENST00000291823

Conserved Domains (2) summary

PTZ00024
Location:17 – 352
Blast Score: 315

PTZ00024; cyclin-dependent protein kinase; Provisional

cl09925
Location:11 – 346
Blast Score: 502

PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000019.9 Reference GRCh37.p5 Primary Assembly

Range

40885178..40896094, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000151.1 Alternate HuRef

Range

37320650..37331675, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC010271.8 (74642..85558)	None
genomic	CH471126.1	EAW56960.1
		EAW56961.1
genomic	CQ891383.1	CAH68679.1
genomic	HC007020.1	CBH19315.1
genomic	HC044799.1	CBH30729.1
mRNA	AK057380.1	BAB71458.1
mRNA	AK292228.1	BAF84917.1
mRNA	AK301713.1	BAG63184.1
mRNA	AK302301.1	BAG63641.1
mRNA	BC034501.2	AAH34501.1