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Rack1 receptor for activated C kinase 1 [ Mus musculus (house mouse) ]

Gene ID: 14694, updated on 28-May-2016
Official Symbol
Rack1provided by MGI
Official Full Name
receptor for activated C kinase 1provided by MGI
Primary source
MGI:MGI:101849
See related
Ensembl:ENSMUSG00000020372 Vega:OTTMUSG00000005526
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p205; Gnb2l1; GB-like; AL033335; Gnb2-rs1
Orthologs
Location:
11; 11 B1.2
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (48800360..48806241)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (48613862..48619743)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 pseudogene Neighboring gene predicted gene, 36109 Neighboring gene small nucleolar RNA, C/D box 96A Neighboring gene small nucleolar RNA, C/D box 95 Neighboring gene tripartite motif-containing 41 Neighboring gene nuclear encoded tRNA valine 7 (anticodon CAC)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SH2 domain binding ISO
Inferred from Sequence Orthology
more info
 
cysteine-type endopeptidase activator activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
ion channel inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein kinase C binding ISA
Inferred from Sequence Alignment
more info
PubMed 
protein kinase C binding ISO
Inferred from Sequence Orthology
more info
 
protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
protein tyrosine kinase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
signaling adaptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cellular response to glucose stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
gastrulation IEA
Inferred from Electronic Annotation
more info
 
intracellular signal transduction ISA
Inferred from Sequence Alignment
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
negative regulation of hydrogen peroxide-induced neuron death IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of hydrogen peroxide-induced neuron death ISO
Inferred from Sequence Orthology
more info
 
negative regulation of peptidyl-serine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of phagocytosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein kinase B signaling ISO
Inferred from Sequence Orthology
more info
 
negative regulation of translation ISO
Inferred from Sequence Orthology
more info
 
osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of Golgi to plasma membrane protein transport ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cyclic-nucleotide phosphodiesterase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitochondrial depolarization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
protein localization ISA
Inferred from Sequence Alignment
more info
PubMed 
regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
regulation of establishment of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
regulation of growth IEA
Inferred from Electronic Annotation
more info
 
regulation of translation IEA
Inferred from Electronic Annotation
more info
 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
IRE1-RACK1-PP2A complex ISO
Inferred from Sequence Orthology
more info
 
cell body IDA
Inferred from Direct Assay
more info
PubMed 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
midbody ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
phagocytic cup ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
receptor of activated protein C kinase 1
Names
12-3
activated protein kinase C receptor
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 sequence 1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
guanine nucleotide binding protein related
guanine nucleotide binding protein, beta 2, related sequence 1
guanine nucleotide binding protein, beta-2, related sequence 1
guanine nucleotide-binding protein subunit beta-2-like 1
receptor for activated C kinase
receptor of activated protein kinase C 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008143.3NP_032169.1  receptor of activated protein C kinase 1

    See identical proteins and their annotated locations for NP_032169.1

    Status: PROVISIONAL

    Source sequence(s)
    AK017772
    Consensus CDS
    CCDS24585.1
    UniProtKB/Swiss-Prot
    P68040
    Related
    ENSMUSP00000020640, OTTMUSP00000043241, ENSMUST00000020640, OTTMUST00000012289
    Conserved Domains (2) summary
    COG2319
    Location:2310
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:7311
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    48800360..48806241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p3 CAST/Ei

Genomic

  1. NT_187028.1 Reference GRCm38.p3 CAST/Ei

    Range
    240186..246277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    53382599..53388480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)