Display Settings:

Format

Send to:

Choose Destination

CDAN1 codanin 1 [ Homo sapiens (human) ]

Gene ID: 146059, updated on 12-Dec-2014
Official Symbol
CDAN1provided by HGNC
Official Full Name
codanin 1provided by HGNC
Primary source
HGNC:HGNC:1713
Locus tag
UNQ664/PRO1295
See related
Ensembl:ENSG00000140326; HPRD:08470; MIM:607465; Vega:OTTHUMG00000175801
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DLT; CDA1; CDAI; CDAN1A; PRO1295
Summary
This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]
See CDAN1 in Epigenomics, MapViewer
Location:
15q15.2
Exon count:
28
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 15 NC_000015.10 (42723562..42737219, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (43015760..43029417, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene myosin, light chain 12B, regulatory pseudogene Neighboring gene eukaryotic translation initiation factor 4E binding protein 2 pseudogene 2 Neighboring gene StAR-related lipid transfer (START) domain containing 9 Neighboring gene uncharacterized LOC102724445 Neighboring gene tau tubulin kinase 2 Neighboring gene keratin, type II cytoskeletal 8-like

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
chromatin assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromatin organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
endomembrane system IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 
Preferred Names
codanin-1
Names
codanin-1
discs lost homolog
congenital dyserythropoietic anemia, type I

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012491.1 

    Range
    5001..18658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138477.2NP_612486.2  codanin-1

    See proteins identical to NP_612486.2

    Status: REVIEWED

    Source sequence(s)
    AF525398, BC001092, BC052568
    Consensus CDS
    CCDS32209.1
    UniProtKB/Swiss-Prot
    Q8IWY9
    Related
    ENSP00000348564, OTTHUMP00000254143, ENST00000356231, OTTHUMT00000431103
    Conserved Domains (1) summary
    pfam15296
    Location:782901
    Codanin-1_C; Codanin-1 C-terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000015.10 

    Range
    42723562..42737219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005254176.2XP_005254233.1  

    Conserved Domains (1) summary
    pfam15296
    Location:783902
    Codanin-1_C; Codanin-1 C-terminus
  2. XM_005254177.1XP_005254234.1  

    Conserved Domains (1) summary
    pfam15296
    Location:783902
    Codanin-1_C; Codanin-1 C-terminus
  3. XM_005254178.1XP_005254235.1  

    Conserved Domains (1) summary
    pfam15296
    Location:783902
    Codanin-1_C; Codanin-1 C-terminus

RNA

  1. XR_429444.1 RNA Sequence

Alternate CHM1_1.1

Genomic

  1. NC_018926.2 

    Range
    43134131..43147791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000147.1 

    Range
    19864346..19878007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)