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Ggh gamma-glutamyl hydrolase [ Mus musculus (house mouse) ]

Gene ID: 14590, updated on 28-May-2016
Official Symbol
Gghprovided by MGI
Official Full Name
gamma-glutamyl hydrolaseprovided by MGI
Primary source
MGI:MGI:1329035
See related
Ensembl:ENSMUSG00000073987
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
gamma-GH
Orthologs
Location:
4; 4 A3
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (20041987..20066111)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (19969199..19993258)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105247101 Neighboring gene tocopherol (alpha) transfer protein Neighboring gene small cell adhesion glycoprotein pseudogene Neighboring gene Na+/K+ transporting ATPase interacting 3 Neighboring gene tubulin, alpha 4A pseudogene

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
gamma-glutamyl-peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
gamma-glutamyl-peptidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
omega peptidase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
response to drug ISO
Inferred from Sequence Orthology
more info
 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
response to insulin ISO
Inferred from Sequence Orthology
more info
 
response to zinc ion ISO
Inferred from Sequence Orthology
more info
 
tetrahydrofolylpolyglutamate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
lysosome TAS
Traceable Author Statement
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
gamma-glutamyl hydrolase
Names
FGPH
GH
conjugase
folylpolyglutamate hydrolase
gamma-Glu-x carboxypeptidase
NP_034411.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010281.2NP_034411.2  gamma-glutamyl hydrolase precursor

    See identical proteins and their annotated locations for NP_034411.2

    Status: VALIDATED

    Source sequence(s)
    AI840300, AI846732, AL732527, BB610405, BE859353, CO044650
    Consensus CDS
    CCDS51126.1
    UniProtKB/Swiss-Prot
    Q9Z0L8
    Related
    ENSMUSP00000095843, OTTMUSP00000006742, ENSMUST00000098242, OTTMUST00000014510
    Conserved Domains (2) summary
    pfam07722
    Location:34245
    Peptidase_C26; Peptidase C26
    cl00020
    Location:36305
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    20041987..20066111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537619.2XP_006537682.1  

    Conserved Domains (2) summary
    pfam07722
    Location:34233
    Peptidase_C26; Peptidase C26
    cl00020
    Location:36231
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    19800007..19824562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)