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Gfi1b growth factor independent 1B [ Mus musculus (house mouse) ]

Gene ID: 14582, updated on 8-May-2016
Official Symbol
Gfi1bprovided by MGI
Official Full Name
growth factor independent 1Bprovided by MGI
Primary source
MGI:MGI:1276578
See related
Ensembl:ENSMUSG00000026815 Vega:OTTMUSG00000011746
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gfi-1B
Orthologs
Location:
2; 2 A3
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (28609450..28621982, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (28464970..28477502, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene carboxyl ester lipase Neighboring gene general transcription factor IIIC, polypeptide 5 Neighboring gene tuberous sclerosis 1 Neighboring gene sperm acrosome associated 9 Neighboring gene adenylate kinase 8

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
hemopoiesis IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of histone H3-K4 methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of granulocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of histone H3-K9 methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of histone H3-K4 methylation IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
zinc finger protein Gfi-1b
Names
growth factor independent protein 1B

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160406.1NP_001153878.1  zinc finger protein Gfi-1b isoform 2

    See identical proteins and their annotated locations for NP_001153878.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an additional segment in the CDS, as compared to variant 1. The resulting isoform (2) is longer but has identical N- and C_termini, as compared to isoform 1.
    Source sequence(s)
    BB734623, BC145238, W65842
    Consensus CDS
    CCDS50549.1
    UniProtKB/TrEMBL
    B7ZNH2
    Related
    ENSMUSP00000128052, ENSMUST00000164290
    Conserved Domains (3) summary
    COG5048
    Location:263340
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:295320
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:255275
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_008114.3NP_032140.1  zinc finger protein Gfi-1b isoform 1

    See identical proteins and their annotated locations for NP_032140.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes a dominant isoform (1).
    Source sequence(s)
    BB734623, BC132367, W65842
    Consensus CDS
    CCDS15843.1
    UniProtKB/Swiss-Prot
    O70237
    Related
    ENSMUSP00000028156, OTTMUSP00000012517, ENSMUST00000028156, OTTMUST00000027549
    Conserved Domains (3) summary
    COG5048
    Location:230307
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:262287
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:222242
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    28609450..28621982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    28313956..28326488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)