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    Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial [ Mus musculus (house mouse) ]

    Gene ID: 14571, updated on 26-Feb-2013
    Official Symbol
    Gpd2provided by MGI
    Official Full Name
    glycerol phosphate dehydrogenase 2, mitochondrialprovided by MGI
    Primary source
    MGI:99778
    See related
    Ensembl:ENSMUSG00000026827; Vega:OTTMUSG00000012561
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GPDH; Gdm1; Gpd-m; Gpdh-m; TISP38; AA408484; AI448216; AU021455; AW494132
    Location :
    2 C1.1; 2 31.66 cM
    Sequence :
    Chromosome: 2; NC_000068.7 (57237678..57370719)
    See Gpd2 in Epigenomics, MapViewer

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930555B11 gene Neighboring gene transfer RNA alanine (anticodon CGC) Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene RIKEN cDNA A930012O16 gene Neighboring gene cytoskeleton associated protein 2 pseudogene Neighboring gene predicted gene 13531 Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    glycerol-3-phosphate dehydrogenase [NAD+] activity ISO
    Inferred from Sequence Orthology
    more info
     
    glycerol-3-phosphate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    NADH metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    gluconeogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycerol-3-phosphate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycerol-3-phosphate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    glycerol-3-phosphate dehydrogenase complex TAS
    Traceable Author Statement
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    glycerol-3-phosphate dehydrogenase, mitochondrial
    Names
    glycerol-3-phosphate dehydrogenase, mitochondrial
    FAD-linked glycerol-3-phosphate dehydrogenase
    glycerol phosphate dehydrogenase 1, mitochondrial
    glycerol-3-phosphate dehydrogenase 2, mitochondrial
    NP_001139292.1
    NP_034404.3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145820.1NP_001139292.1  glycerol-3-phosphate dehydrogenase, mitochondrial precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
      Source sequence(s)
      AK032044, AK080240, AK144716
      Consensus CDS
      CCDS16045.1
      UniProtKB/Swiss-Prot
      Q64521
      Related
      ENSMUSP00000130992, ENSMUST00000169687
      Conserved Domains (4) summary
      cd00051
      Location:627689
      Blast Score: 145
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      COG0578
      Location:57599
      Blast Score: 1090
      GlpA; Glycerol-3-phosphate dehydrogenase [Energy production and conversion]
      pfam13499
      Location:634688
      Blast Score: 113
      EF_hand_5; EF-hand domain pair
      TIGR03378
      Location:70107
      Blast Score: 107
      glycerol3P_GlpB; glycerol-3-phosphate dehydrogenase, anaerobic, B subunit
    2. NM_010274.3NP_034404.3  glycerol-3-phosphate dehydrogenase, mitochondrial precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
      Source sequence(s)
      AK032044, AK080240, AK144716, BY238564
      Consensus CDS
      CCDS16045.1
      UniProtKB/Swiss-Prot
      Q64521
      Related
      ENSMUSP00000028167, ENSMUST00000028167
      Conserved Domains (4) summary
      cd00051
      Location:627689
      Blast Score: 145
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      COG0578
      Location:57599
      Blast Score: 1090
      GlpA; Glycerol-3-phosphate dehydrogenase [Energy production and conversion]
      pfam13499
      Location:634688
      Blast Score: 113
      EF_hand_5; EF-hand domain pair
      TIGR03378
      Location:70107
      Blast Score: 107
      glycerol3P_GlpB; glycerol-3-phosphate dehydrogenase, anaerobic, B subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p1 C57BL/6J

      Range
      57237678..57370719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000024.1 Alternate Mm_Celera

      Range
      58979703..59113189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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