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Fdft1 farnesyl diphosphate farnesyl transferase 1 [ Mus musculus (house mouse) ]

Gene ID: 14137, updated on 28-May-2016
Official Symbol
Fdft1provided by MGI
Official Full Name
farnesyl diphosphate farnesyl transferase 1provided by MGI
Primary source
MGI:MGI:102706
See related
Ensembl:ENSMUSG00000021273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SS; SQS
Orthologs
Location:
14 D1; 14 33.24 cM
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 14 NC_000080.6 (63145150..63179655, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (63763987..63796630, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35908 Neighboring gene predicted gene, 36025 Neighboring gene tubulin, alpha 3B pseudogene Neighboring gene cathepsin B Neighboring gene nei like 2 (E. coli) Neighboring gene GATA binding protein 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
farnesyl-diphosphate farnesyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
squalene synthase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
cholesterol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 
farnesyl diphosphate metabolic process ISO
Inferred from Sequence Orthology
more info
 
isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
lipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
steroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
steroid metabolic process IEA
Inferred from Electronic Annotation
more info
 
sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
squalene synthase
Names
FPP:FPP farnesyltransferase
farnesyl-diphosphate farnesyltransferase
NP_034321.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010191.3NP_034321.2  squalene synthase

    See identical proteins and their annotated locations for NP_034321.2

    Status: VALIDATED

    Source sequence(s)
    AK136159, BC054722
    Consensus CDS
    CCDS27198.1
    UniProtKB/Swiss-Prot
    P53798
    Related
    ENSMUSP00000055313, ENSMUST00000054963
    Conserved Domains (1) summary
    cd00683
    Location:41321
    Trans_IPPS_HH; Trans-Isoprenyl Diphosphate Synthases, head-to-head

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p3 C57BL/6J

    Range
    63145150..63179655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518546.2XP_006518609.1  

    Conserved Domains (1) summary
    cd00683
    Location:41321
    Trans_IPPS_HH; Trans-Isoprenyl Diphosphate Synthases, head-to-head
  2. XM_011244951.1XP_011243253.1  

    Conserved Domains (1) summary
    cd00683
    Location:85365
    Trans_IPPS_HH; Trans-Isoprenyl Diphosphate Synthases, head-to-head
  3. XM_006518547.2XP_006518610.1  

    Conserved Domains (1) summary
    cl00210
    Location:1221
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

Alternate Mm_Celera

Genomic

  1. AC_000036.1 Alternate Mm_Celera

    Range
    60907922..60941524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)