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Fcgr3 Fc receptor, IgG, low affinity III [ Mus musculus (house mouse) ]

Gene ID: 14131, updated on 17-May-2016
Official Symbol
Fcgr3provided by MGI
Official Full Name
Fc receptor, IgG, low affinity IIIprovided by MGI
Primary source
MGI:MGI:95500
See related
Ensembl:ENSMUSG00000059498 Vega:OTTMUSG00000035155
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CD16
Location:
1 H3; 1 78.8 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (171051169..171065933, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (172981300..172989534, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA leucine 3 (anticodon CAG) Neighboring gene nuclear encoded tRNA glycine 4 (anticodon GCC) Neighboring gene nuclear encoded tRNA glutamic acid 5 (anticodon CTC) Neighboring gene nuclear encoded tRNA glycine 1 (anticodon TCC) Neighboring gene microRNA 6546 Neighboring gene nuclear encoded tRNA aspartic acid 3 (anticodon GTC) Neighboring gene nuclear encoded tRNA glycine 12 (anticodon GCC) Neighboring gene nuclear encoded tRNA leucine 6 (anticodon CAG)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • FCGR activation, organism-specific biosystem (from REACTOME)
    FCGR activation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Fcgamma receptor (FCGR) dependent phagocytosis, organism-specific biosystem (from REACTOME)
    Fcgamma receptor (FCGR) dependent phagocytosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Leishmaniasis, organism-specific biosystem (from KEGG)
    Leishmaniasis, organism-specific biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
  • Leishmaniasis, conserved biosystem (from KEGG)
    Leishmaniasis, conserved biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
  • Osteoclast differentiation, organism-specific biosystem (from KEGG)
    Osteoclast differentiation, organism-specific biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
  • Osteoclast differentiation, conserved biosystem (from KEGG)
    Osteoclast differentiation, conserved biosystemThe osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways...
  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Regulation of actin dynamics for phagocytic cup formation, organism-specific biosystem (from REACTOME)
    Regulation of actin dynamics for phagocytic cup formation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Role of phospholipids in phagocytosis, organism-specific biosystem (from REACTOME)
    Role of phospholipids in phagocytosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Staphylococcus aureus infection, organism-specific biosystem (from KEGG)
    Staphylococcus aureus infection, organism-specific biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
  • Staphylococcus aureus infection, conserved biosystem (from KEGG)
    Staphylococcus aureus infection, conserved biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
IgG binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
IgG receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
IgG receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
low affinity immunoglobulin gamma Fc region receptor III
Names
Fc gamma receptor III
Fcg receptor III
FcgammaRIII
fc-gamma RIII
fcRIII
igG Fc receptor III

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010188.5NP_034318.2  low affinity immunoglobulin gamma Fc region receptor III precursor

    See identical proteins and their annotated locations for NP_034318.2

    Status: VALIDATED

    Source sequence(s)
    AC115959, AK151557, BY199827
    Consensus CDS
    CCDS15477.2
    UniProtKB/TrEMBL
    A0A0B4J1M6
    Related
    ENSMUSP00000131938, OTTMUSP00000048932, ENSMUST00000164044, OTTMUST00000089518
    Conserved Domains (2) summary
    smart00410
    Location:129205
    IG_like; Immunoglobulin like
    cl11960
    Location:123205
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    171051169..171065933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496659.2XP_006496722.1  

    See identical proteins and their annotated locations for XP_006496722.1

    UniProtKB/TrEMBL
    A0A0B4J1M6
    Conserved Domains (2) summary
    smart00410
    Location:129205
    IG_like; Immunoglobulin like
    cl11960
    Location:123205
    Ig; Immunoglobulin domain
  2. XM_006496658.2XP_006496721.1  

    See identical proteins and their annotated locations for XP_006496721.1

    UniProtKB/TrEMBL
    A0A0B4J1M6
    Conserved Domains (2) summary
    smart00410
    Location:129205
    IG_like; Immunoglobulin like
    cl11960
    Location:123205
    Ig; Immunoglobulin domain
  3. XM_006496660.2XP_006496723.1  

    See identical proteins and their annotated locations for XP_006496723.1

    UniProtKB/TrEMBL
    E9PUV2
    Conserved Domains (2) summary
    smart00410
    Location:128204
    IG_like; Immunoglobulin like
    cl11960
    Location:122204
    Ig; Immunoglobulin domain
  4. XM_006496661.2XP_006496724.1  

    See identical proteins and their annotated locations for XP_006496724.1

    UniProtKB/TrEMBL
    E9PUV2
    Related
    ENSMUSP00000131836, OTTMUSP00000048933, ENSMUST00000169017, OTTMUST00000089519
    Conserved Domains (2) summary
    smart00410
    Location:128204
    IG_like; Immunoglobulin like
    cl11960
    Location:122204
    Ig; Immunoglobulin domain

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    173499171..173507755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)