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Ikbkap inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 140934, updated on 17-May-2016
Official Symbol
Ikbkapprovided by RGD
Official Full Name
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated proteinprovided by RGD
Primary source
RGD:620072
See related
Ensembl:ENSRNOG00000016725
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
mutation of gene is associated with autosomal recessive disorder familial dysautonomia (FD) [RGD, Feb 2006]
Orthologs
Location:
5q24
Exon count:
37
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (73503406..73552798, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (77661315..77710707, complement)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene actin-like 7b Neighboring gene actin-like 7a Neighboring gene family with sequence similarity 206, member A Neighboring gene catenin alpha-like 1

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II core binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase II core binding ISO
Inferred from Sequence Orthology
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
phosphorylase kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 
phosphorylase kinase regulator activity ISO
Inferred from Sequence Orthology
more info
 
phosphorylase kinase regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
I-kappaB phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
tRNA wobble uridine modification IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Elongator holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 
Elongator holoenzyme complex ISO
Inferred from Sequence Orthology
more info
 
Elongator holoenzyme complex ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 
histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
transcription elongation factor complex IEA
Inferred from Electronic Annotation
more info
 
transcription elongation factor complex ISO
Inferred from Sequence Orthology
more info
 
transcription elongation factor complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
elongator complex protein 1
Names
ELP1
IKK complex-associated protein
ikappaB kinase complex-associated protein
inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080899.1NP_543175.1  elongator complex protein 1

    See identical proteins and their annotated locations for NP_543175.1

    Status: PROVISIONAL

    Source sequence(s)
    AF388201
    UniProtKB/Swiss-Prot
    Q8VHU4
    Related
    ENSRNOP00000022836, ENSRNOT00000022836
    Conserved Domains (3) summary
    COG0457
    Location:8741099
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    COG5290
    Location:711275
    COG5290; IkappaB kinase complex, IKAP component [Transcription]
    pfam04762
    Location:1953
    IKI3; IKI3 family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    73503406..73552798 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    70310353..70359709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)