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Phkg2 phosphorylase kinase gamma subunit 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 140671, updated on 8-May-2016
Official Symbol
Phkg2provided by RGD
Official Full Name
phosphorylase kinase gamma subunit 2provided by RGD
Primary source
RGD:620024
See related
Ensembl:ENSRNOG00000018725
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
phosphorylase kinase catalytic subunit isoform; catalyzes the phosphorylation and activation of glycogen phosphorylase [RGD, Feb 2006]
Orthologs
Location:
1q36
Exon count:
11
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (199019304..199032047)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (206027201..206039931)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene Snf2-related CREBBP activator protein Neighboring gene transmembrane protein 265 Neighboring gene coiled-coil domain containing 189 Neighboring gene ring finger protein 40

  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Glucagon signaling pathway, organism-specific biosystem (from KEGG)
    Glucagon signaling pathway, organism-specific biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucagon signaling pathway, conserved biosystem (from KEGG)
    Glucagon signaling pathway, conserved biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucose metabolism, organism-specific biosystem (from REACTOME)
    Glucose metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Glycogen Metabolism, organism-specific biosystem (from WikiPathways)
    Glycogen Metabolism, organism-specific biosystemGlycogen is a very large, branched polymer of glucose residues. Within skeletal musle and liver glucose is stored as glycogen. In the liver, glycogen synthesis and degradation are regulated to mainta...
  • Glycogen breakdown (glycogenolysis), organism-specific biosystem (from REACTOME)
    Glycogen breakdown (glycogenolysis), organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Insulin signaling pathway, organism-specific biosystem (from KEGG)
    Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • Insulin signaling pathway, conserved biosystem (from KEGG)
    Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • Metabolism, organism-specific biosystem (from REACTOME)
    Metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Metabolism of carbohydrates, organism-specific biosystem (from REACTOME)
    Metabolism of carbohydrates, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • PKA-HCG-Glycogen Syntase, organism-specific biosystem (from WikiPathways)
    PKA-HCG-Glycogen Syntase, organism-specific biosystem
    PKA-HCG-Glycogen Syntase

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enzyme binding IDA
Inferred from Direct Assay
more info
PubMed 
phosphorylase kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
glycogen metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
phosphorylase kinase complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
phosphorylase b kinase gamma catalytic chain, liver/testis isoform
Names
PHK-gamma-LT
PHK-gamma-T
phosphorylase b kinase gamma catalytic chain, testis/liver isoform
phosphorylase b kinase gamma catalytic chain, testis/liver isoform-like
phosphorylase kinase subunit gamma 2
phosphorylase kinase subunit gamma-2
phosphorylase kinase, gamma 2 (testis)
serine/threonine-protein kinase PHKG2
NP_542151.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080584.4NP_542151.1  phosphorylase b kinase gamma catalytic chain, liver/testis isoform

    See identical proteins and their annotated locations for NP_542151.1

    Status: PROVISIONAL

    Source sequence(s)
    M73808
    UniProtKB/Swiss-Prot
    P31325
    Related
    ENSRNOP00000025419, ENSRNOT00000025419
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14181
    Location:13291
    STKc_PhKG2; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma 2 subunit

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    199019304..199032047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008759855.1XP_008758077.1  

    See identical proteins and their annotated locations for XP_008758077.1

    UniProtKB/Swiss-Prot
    P31325
    Related
    ENSRNOP00000072734, ENSRNOT00000087142
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14181
    Location:13291
    STKc_PhKG2; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma 2 subunit
  2. XM_008759856.1XP_008758078.1  

    See identical proteins and their annotated locations for XP_008758078.1

    UniProtKB/Swiss-Prot
    P31325
    Conserved Domains (2) summary
    smart00220
    Location:24291
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14181
    Location:13291
    STKc_PhKG2; Catalytic domain of the Serine/Threonine Kinase, Phosphorylase kinase Gamma 2 subunit

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    179836521..179848906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)