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Ubox5 U box domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 140629, updated on 8-May-2016
Official Symbol
Ubox5provided by MGI
Official Full Name
U box domain containing 5provided by MGI
Primary source
MGI:MGI:2154658
See related
Ensembl:ENSMUSG00000027300 Vega:OTTMUSG00000015515
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
UIP5; Rnf37; Ube7ip5; Ubce7ip5; 1500010O06Rik; C330018L13Rik
Orthologs
Location:
2; 2 F3
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (130589996..130630038, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (130415738..130455722, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene oxytocin Neighboring gene arginine vasopressin Neighboring gene FAST kinase domains 5 Neighboring gene leucine zipper, putative tumor suppressor family member 3 Neighboring gene DDRGK domain containing 1 Neighboring gene predicted gene, 30229

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
    Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
  • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
    Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-0 gamma-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
coenzyme F420-2 alpha-glutamyl ligase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, elongating IEA
Inferred from Electronic Annotation
more info
 
protein-glycine ligase activity, initiating IEA
Inferred from Electronic Annotation
more info
 
ribosomal S6-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glutamic acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
tubulin-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-ubiquitin ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
protein polyubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
RING finger protein 37
Names
U-box domain-containing protein 5
UbcM4-interacting protein 5
ubiquitin conjugating enzyme 7 interacting protein 5
ubiquitin-conjugating enzyme 7-interacting protein 5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001255993.1NP_001242922.1  RING finger protein 37

    See identical proteins and their annotated locations for NP_001242922.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longest transcript. Variants 1-3 encode the same protein.
    Source sequence(s)
    AK034114, AK158052, AL731707, AW060426
    Consensus CDS
    CCDS16747.1
    UniProtKB/Swiss-Prot
    Q925F4
    UniProtKB/TrEMBL
    Q3TZ72, Q543N0
    Conserved Domains (2) summary
    cd00162
    Location:480529
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam04564
    Location:259337
    U-box; U-box domain
  2. NM_001255994.1NP_001242923.1  RING finger protein 37

    See identical proteins and their annotated locations for NP_001242923.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AF360997, AL731707, AW060426
    Consensus CDS
    CCDS16747.1
    UniProtKB/Swiss-Prot
    Q925F4
    UniProtKB/TrEMBL
    Q543N0
    Related
    ENSMUSP00000028761, OTTMUSP00000016527, ENSMUST00000028761, OTTMUST00000036839
    Conserved Domains (2) summary
    cd00162
    Location:480529
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam04564
    Location:259337
    U-box; U-box domain
  3. NM_080562.5NP_542129.2  RING finger protein 37

    See identical proteins and their annotated locations for NP_542129.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AK034114, AL731707, AW060426
    Consensus CDS
    CCDS16747.1
    UniProtKB/Swiss-Prot
    Q925F4
    UniProtKB/TrEMBL
    Q543N0
    Conserved Domains (2) summary
    cd00162
    Location:480529
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam04564
    Location:259337
    U-box; U-box domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    130589996..130630038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    131814420..131854490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)