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Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 140486, updated on 21-May-2016
Official Symbol
Igf2bp1provided by MGI
Official Full Name
insulin-like growth factor 2 mRNA binding protein 1provided by MGI
Primary source
MGI:MGI:1890357
See related
Ensembl:ENSMUSG00000013415 Vega:OTTMUSG00000001937
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zbp1; Crdbp; IMP-1; ZBP-1; CRD-BP; Neilsen; AL024068; AW549074; D11Moh45; mir-3063; D11Moh40e; D030026A21Rik
Orthologs
Location:
11 D; 11 59.08 cM
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (95957163..96005944, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (95818477..95867258, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4833417C18 gene Neighboring gene transfer RNA glutamine (anticodon UUG) Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 2 Neighboring gene microRNA 3063 Neighboring gene gastric inhibitory polypeptide Neighboring gene SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
mRNA 3'-UTR binding ISO
Inferred from Sequence Orthology
more info
 
mRNA 5'-UTR binding ISO
Inferred from Sequence Orthology
more info
 
mRNA binding ISO
Inferred from Sequence Orthology
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
translation regulator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
CRD-mediated mRNA stabilization ISO
Inferred from Sequence Orthology
more info
 
RNA localization ISO
Inferred from Sequence Orthology
more info
 
mRNA transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of translation ISO
Inferred from Sequence Orthology
more info
 
neuronal stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
pallium cell proliferation in forebrain IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mRNA stability involved in response to stress ISO
Inferred from Sequence Orthology
more info
 
regulation of translation IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
CRD-mediated mRNA stability complex ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
intracellular ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
insulin-like growth factor 2 mRNA-binding protein 1
Names
IGF-II mRNA-binding protein 1
IGF2 mRNA-binding protein 1
VICKZ family member 1
coding region determinant binding protein
coding region determinant-binding protein
insulin-like growth factor 2 mRNA binding protein 1 dN CRDBP-2
insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP
insulin-like growth factor 2, binding protein 1
zipcode binding protein 1
zipcode-binding protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009951.4NP_034081.1  insulin-like growth factor 2 mRNA-binding protein 1

    See identical proteins and their annotated locations for NP_034081.1

    Status: VALIDATED

    Source sequence(s)
    AL603682, AL606704
    Consensus CDS
    CCDS25286.1
    UniProtKB/Swiss-Prot
    O88477
    Related
    ENSMUSP00000013559, OTTMUSP00000001867, ENSMUST00000013559, OTTMUST00000003877
    Conserved Domains (5) summary
    smart00360
    Location:370
    RRM; RNA recognition motif
    cd00105
    Location:279344
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd12625
    Location:177
    RRM1_IGF2BP1; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
    cd12628
    Location:81156
    RRM2_IGF2BP1; RNA recognition motif 2 in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
    TIGR03665
    Location:412577
    arCOG04150; arCOG04150 universal archaeal KH domain protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    95957163..96005944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    105607858..105656580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)