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Hnmt histamine N-methyltransferase [ Mus musculus (house mouse) ]

Gene ID: 140483, updated on 8-May-2016
Official Symbol
Hnmtprovided by MGI
Official Full Name
histamine N-methyltransferaseprovided by MGI
Primary source
MGI:MGI:2153181
See related
Ensembl:ENSMUSG00000026986 Vega:OTTMUSG00000011800
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI788969; 1500031F01Rik
Orthologs
Location:
2; 2 A3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (24002911..24049757, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (23858431..23904899, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2D 3 pseudogene Neighboring gene speckle-type POZ protein-like Neighboring gene SH3 domain protein 2C, pseudogene 1 Neighboring gene TATA box binding protein like 2 Neighboring gene interleukin 1 family, member 8

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
N-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
histamine N-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
histamine N-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
brain development IBA
Inferred from Biological aspect of Ancestor
more info
 
methylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein targeting to mitochondrion ISO
Inferred from Sequence Orthology
more info
 
regulation of neurotransmitter levels TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
histamine N-methyltransferase
Names
HMT
NP_536710.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080462.2NP_536710.1  histamine N-methyltransferase

    See identical proteins and their annotated locations for NP_536710.1

    Status: VALIDATED

    Source sequence(s)
    AF297037, AK160131, AW456742
    Consensus CDS
    CCDS15731.1
    UniProtKB/Swiss-Prot
    Q91VF2
    UniProtKB/TrEMBL
    A2AQK4
    Related
    ENSMUSP00000062747, OTTMUSP00000012588, ENSMUST00000051416, OTTMUST00000027697
    Conserved Domains (1) summary
    cd02440
    Location:55174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    24002911..24049757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497670.2XP_006497733.1  

    Conserved Domains (1) summary
    cd02440
    Location:67186
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  2. XM_006497671.2XP_006497734.1  

    See identical proteins and their annotated locations for XP_006497734.1

    UniProtKB/Swiss-Prot
    Q91VF2
    UniProtKB/TrEMBL
    A2AQK4
    Related
    ENSMUSP00000110142, OTTMUSP00000012589, ENSMUST00000114498, OTTMUST00000027698
    Conserved Domains (1) summary
    cd02440
    Location:55174
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    23732675..23779256 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)