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Ephx1 epoxide hydrolase 1, microsomal [ Mus musculus (house mouse) ]

Gene ID: 13849, updated on 8-May-2016
Official Symbol
Ephx1provided by MGI
Official Full Name
epoxide hydrolase 1, microsomalprovided by MGI
Primary source
MGI:MGI:95405
See related
Ensembl:ENSMUSG00000038776 Vega:OTTMUSG00000021983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EH; mEH; Eph1; Eph-1; Epxh1
Orthologs
Location:
1 H4; 1 84.48 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (180989556..181017495, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (182919687..182947626, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39715 Neighboring gene left right determination factor 1 Neighboring gene transmembrane protein 63a Neighboring gene RIKEN cDNA 9130409I23 gene Neighboring gene predicted gene, 39716 Neighboring gene ribosomal protein L7 pseudogene Neighboring gene predicted gene, 37406

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
cis-stilbene-oxide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
epoxide hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
aromatic compound catabolic process IEA
Inferred from Electronic Annotation
more info
 
cellular aromatic compound metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to organic cyclic compound IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to toxic substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
epoxide hydrolase 1
Names
epoxide hydratase
microsomal epoxide hydrolase
NP_034275.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001312918.1NP_001299847.1  epoxide hydrolase 1 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC117673, AK018249, AW047588, BY312366
    UniProtKB/Swiss-Prot
    Q9D379
    UniProtKB/TrEMBL
    E9PWK1
    Conserved Domains (2) summary
    pfam00561
    Location:178376
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam06441
    Location:49161
    EHN; Epoxide hydrolase N terminus
  2. NM_010145.3NP_034275.1  epoxide hydrolase 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_034275.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC117673, AK018249, AW047588, BY312366
    Consensus CDS
    CCDS15579.1
    UniProtKB/Swiss-Prot
    Q9D379
    Related
    ENSMUSP00000047551, OTTMUSP00000024696, ENSMUST00000036928, OTTMUST00000052194
    Conserved Domains (2) summary
    pfam00561
    Location:178390
    Abhydrolase_1; alpha/beta hydrolase fold
    pfam06441
    Location:49161
    EHN; Epoxide hydrolase N terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    180989556..181017495 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    188055356..188083565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)