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UBXN2B UBX domain protein 2B [ Homo sapiens (human) ]

Gene ID: 137886, updated on 7-Feb-2016
Official Symbol
UBXN2Bprovided by HGNC
Official Full Name
UBX domain protein 2Bprovided by HGNC
Primary source
HGNC:HGNC:27035
See related
Ensembl:ENSG00000215114; MIM:610686; Vega:OTTHUMG00000164300
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
p37
Orthologs
See UBXN2B in Epigenomics, MapViewer
Location:
8q12.1
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 8 NC_000008.11 (58411264..58451501)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (59323823..59364060)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 110 member B Neighboring gene ribosomal protein L26 pseudogene 26 Neighboring gene uncharacterized LOC101929528 Neighboring gene protein tyrosine phosphatase, non-receptor type 11 pseudogene Neighboring gene uncharacterized LOC105375857 Neighboring gene cytochrome P450 family 7 subfamily A member 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase type 1 regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane fusion IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear envelope reassembly IBA
Inferred from Biological aspect of Ancestor
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of catalytic activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
UBX domain-containing protein 2B
Names
NSFL1 cofactor p37
p97 cofactor p37

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077619.1NP_001071087.1  UBX domain-containing protein 2B

    See identical proteins and their annotated locations for NP_001071087.1

    Status: VALIDATED

    Source sequence(s)
    AK126300, BC113645, U79282
    Consensus CDS
    CCDS43741.1
    UniProtKB/Swiss-Prot
    Q14CS0
    Related
    ENSP00000382507, OTTHUMP00000226407, ENST00000399598, OTTHUMT00000378184
    Conserved Domains (2) summary
    cd01770
    Location:253331
    p47_UBX; p47-like ubiquitin domain
    smart00553
    Location:140232
    SEP; Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p2 Primary Assembly

    Range
    58411264..58451501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251165.1XP_005251222.1  

    See identical proteins and their annotated locations for XP_005251222.1

    Conserved Domains (2) summary
    cd01770
    Location:207285
    p47_UBX; p47-like ubiquitin domain
    cl02662
    Location:146182
    SEP; SEP domain
  2. XM_005251166.1XP_005251223.1  

    UniProtKB/TrEMBL
    E5RJ36
    Conserved Domains (1) summary
    cl02662
    Location:146178
    SEP; SEP domain

RNA

  1. XR_242453.1 RNA Sequence

    Related
    ENST00000523409, OTTHUMT00000378188

Alternate CHM1_1.1

Genomic

  1. NC_018919.2 Alternate CHM1_1.1

    Range
    59375721..59415949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)