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Elf5 E74-like factor 5 [ Mus musculus (house mouse) ]

Gene ID: 13711, updated on 17-May-2016
Official Symbol
Elf5provided by MGI
Official Full Name
E74-like factor 5provided by MGI
Primary source
MGI:MGI:1335079
See related
Ensembl:ENSMUSG00000027186 Vega:OTTMUSG00000014860
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESE-2; ESE-5; ESE-5.
Orthologs
Location:
2; 2 E3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (103411693..103450989)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (103252255..103291146)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A930006I01 gene Neighboring gene cDNA sequence BC016548 Neighboring gene catalase Neighboring gene uncharacterized LOC105244251 Neighboring gene ankyrin repeat and BTB (POZ) domain containing 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Prolactin signaling pathway, organism-specific biosystem (from KEGG)
    Prolactin signaling pathway, organism-specific biosystemProlactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological functions including osmoregulation, lactation, reproduction, growth and development, endocrinology and meta...
  • Prolactin signaling pathway, conserved biosystem (from KEGG)
    Prolactin signaling pathway, conserved biosystemProlactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological functions including osmoregulation, lactation, reproduction, growth and development, endocrinology and meta...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
ectoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ectodermal cell fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
mammary gland epithelial cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
somatic stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ETS-related transcription factor Elf-5
Names
Epithelium specific Ets-2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145813.1NP_001139285.1  ETS-related transcription factor Elf-5

    See identical proteins and their annotated locations for NP_001139285.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    AK132484, AL773505
    Consensus CDS
    CCDS16477.1
    UniProtKB/Swiss-Prot
    Q8VDK3
    UniProtKB/TrEMBL
    Q3V1F7
    Related
    ENSMUSP00000126941, ENSMUST00000164172
    Conserved Domains (2) summary
    cd08538
    Location:39122
    SAM_PNT-ESE-2-like; Sterile alpha motif (SAM)/Pointed domain of ESE-2 like ETS transcriptional regulators
    smart00413
    Location:162246
    ETS; erythroblast transformation specific domain
  2. NM_010125.3NP_034255.2  ETS-related transcription factor Elf-5

    See identical proteins and their annotated locations for NP_034255.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    AF049702, AK132484, AK145214, AL773505
    Consensus CDS
    CCDS16477.1
    UniProtKB/Swiss-Prot
    Q8VDK3
    UniProtKB/TrEMBL
    Q3ULZ4, Q3V1F7
    Related
    ENSMUSP00000028609, OTTMUSP00000015784, ENSMUST00000028609, OTTMUST00000035295
    Conserved Domains (2) summary
    cd08538
    Location:39122
    SAM_PNT-ESE-2-like; Sterile alpha motif (SAM)/Pointed domain of ESE-2 like ETS transcriptional regulators
    smart00413
    Location:162246
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    103411693..103450989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498704.1XP_006498767.1  

    Conserved Domains (2) summary
    cd08538
    Location:70153
    SAM_PNT-ESE-2-like; Sterile alpha motif (SAM)/Pointed domain of ESE-2 like ETS transcriptional regulators
    smart00413
    Location:193277
    ETS; erythroblast transformation specific domain
  2. XM_006498705.1XP_006498768.1  

    See identical proteins and their annotated locations for XP_006498768.1

    UniProtKB/Swiss-Prot
    Q8VDK3
    UniProtKB/TrEMBL
    Q3V1F7
    Conserved Domains (2) summary
    cd08538
    Location:39122
    SAM_PNT-ESE-2-like; Sterile alpha motif (SAM)/Pointed domain of ESE-2 like ETS transcriptional regulators
    smart00413
    Location:162246
    ETS; erythroblast transformation specific domain

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    104658179..104697597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)