Format

Send to:

Choose Destination

Elf3 E74-like factor 3 [ Mus musculus (house mouse) ]

Gene ID: 13710, updated on 8-May-2016
Official Symbol
Elf3provided by MGI
Official Full Name
E74-like factor 3provided by MGI
Primary source
MGI:MGI:1101781
See related
Ensembl:ENSMUSG00000003051 Vega:OTTMUSG00000049800
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESX; jen; ESE-1
Orthologs
Location:
1; 1 F
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (135253574..135258565, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (137150151..137155049, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41955 Neighboring gene nucleosome assembly protein 1-like 1 pseudogene Neighboring gene arginyl aminopeptidase (aminopeptidase B) Neighboring gene myeloma-overexpressed gene 2 protein homolog pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
anatomical structure morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
blastocyst development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
embryo development IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
mammary gland involution IDA
Inferred from Direct Assay
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IC
Inferred by Curator
more info
PubMed 
Preferred Names
ETS-related transcription factor Elf-3
Names
elf3
epithelial-restricted with serine box
epithelium-restricted Ets protein ESX
epithelium-specific Ets transcription factor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163131.1NP_001156603.1  ETS-related transcription factor Elf-3 isoform 1

    See identical proteins and their annotated locations for NP_001156603.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC130277, BC145380
    Consensus CDS
    CCDS48372.1
    UniProtKB/Swiss-Prot
    Q3UPW2
    Related
    ENSMUSP00000003135, OTTMUSP00000068569, ENSMUST00000003135, OTTMUST00000126843
    Conserved Domains (2) summary
    cd08537
    Location:74151
    SAM_PNT-ESE-1-like; Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators
    smart00413
    Location:292379
    ETS; erythroblast transformation specific domain
  2. NM_007921.3NP_031947.1  ETS-related transcription factor Elf-3 isoform 2

    See identical proteins and their annotated locations for NP_031947.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The resulting isoform (2) is shorter compared to isoform 1.
    Source sequence(s)
    AC130277, BC138692
    Consensus CDS
    CCDS78689.1
    UniProtKB/Swiss-Prot
    Q3UPW2
    Related
    ENSMUSP00000139769, OTTMUSP00000068570, ENSMUST00000185752, OTTMUST00000126844
    Conserved Domains (2) summary
    cd08537
    Location:52131
    SAM_PNT-ESE-1-like; Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators
    smart00413
    Location:272359
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    135253574..135258565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529125.1XP_006529188.1  

    Conserved Domains (2) summary
    cd08537
    Location:126205
    SAM_PNT-ESE-1-like; Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators
    smart00413
    Location:346433
    ETS; erythroblast transformation specific domain
  2. XM_006529124.1XP_006529187.1  

    Conserved Domains (2) summary
    cd08537
    Location:148225
    SAM_PNT-ESE-1-like; Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators
    smart00413
    Location:366453
    ETS; erythroblast transformation specific domain

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    137878901..137883796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)