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Eif3a eukaryotic translation initiation factor 3, subunit A [ Mus musculus (house mouse) ]

Gene ID: 13669, updated on 8-May-2016
Official Symbol
Eif3aprovided by MGI
Official Full Name
eukaryotic translation initiation factor 3, subunit Aprovided by MGI
Primary source
MGI:MGI:95301
See related
Ensembl:ENSMUSG00000024991
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Csma; Eif3; Eif3s10; mKIAA0139; A830012B05Rik
Orthologs
Location:
19; 19 D
Exon count:
22
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (60761116..60790693, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (60837019..60866596, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34459 Neighboring gene predicted gene, 34406 Neighboring gene nanos homolog 1 (Drosophila) Neighboring gene predicted gene, 38437 Neighboring gene small nucleolar RNA, H/ACA box 19 Neighboring gene family with sequence similarity 45, member A Neighboring gene predicted gene 15959 Neighboring gene sideroflexin 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to translation initiation factor activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
IRES-dependent viral translational initiation ISO
Inferred from Sequence Orthology
more info
 
formation of cytoplasmic translation initiation complex IDA
Inferred from Direct Assay
more info
PubMed 
formation of cytoplasmic translation initiation complex ISO
Inferred from Sequence Orthology
more info
 
negative regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
translational initiation IEA
Inferred from Electronic Annotation
more info
 
viral translational termination-reinitiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
eukaryotic translation initiation factor 3 complex IDA
Inferred from Direct Assay
more info
PubMed 
eukaryotic translation initiation factor 3 complex ISO
Inferred from Sequence Orthology
more info
 
eukaryotic translation initiation factor 3 complex, eIF3m IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
microtubule ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
eukaryotic translation initiation factor 3 subunit A
Names
EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN)
centrosomin
eIF-3-theta
eIF3 p167
eIF3 p180
eIF3 p185
eIF3a
eukaryotic translation initiation factor 3, subunit 10 (theta)
p162

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010123.3NP_034253.3  eukaryotic translation initiation factor 3 subunit A

    See identical proteins and their annotated locations for NP_034253.3

    Status: VALIDATED

    Source sequence(s)
    AC163019, AK013070, AK145132, AK162784, U14172
    Consensus CDS
    CCDS38035.1
    UniProtKB/Swiss-Prot
    P23116
    UniProtKB/TrEMBL
    Q3TRH1, Q3UM46
    Related
    ENSMUSP00000025955, ENSMUST00000025955
    Conserved Domains (5) summary
    pfam05750
    Location:8821111
    Rubella_Capsid; Rubella capsid protein
    smart00753
    Location:426498
    PAM; PCI/PINT associated module
    pfam09311
    Location:543717
    Rab5-bind; Rabaptin-like protein
    cl00788
    Location:610707
    MttA_Hcf106; mttA/Hcf106 family
    cl21478
    Location:558645
    Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

    Range
    60761116..60790693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000041.1 Alternate Mm_Celera

    Range
    62970389..62999944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)