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Efna3 ephrin A3 [ Mus musculus (house mouse) ]

Gene ID: 13638, updated on 28-May-2016
Official Symbol
Efna3provided by MGI
Official Full Name
ephrin A3provided by MGI
Primary source
MGI:MGI:106644
See related
Ensembl:ENSMUSG00000028039 Vega:OTTMUSG00000028865
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Epl3; EFL-2; Ehk1-L; LERK-3; AW494418
Orthologs
Location:
3 F1; 3 39.06 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (89313899..89322960, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (89118873..89126801, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene ephrin A1 Neighboring gene predicted gene, 33845 Neighboring gene predicted gene, 34014 Neighboring gene predicted gene 15998 Neighboring gene predicted gene, 34118 Neighboring gene ephrin A4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Axon guidance, organism-specific biosystem (from KEGG)
    Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, conserved biosystem (from KEGG)
    Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, organism-specific biosystem (from REACTOME)
    Axon guidance, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • EPH-Ephrin signaling, organism-specific biosystem (from REACTOME)
    EPH-Ephrin signaling, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • EPH-ephrin mediated repulsion of cells, organism-specific biosystem (from REACTOME)
    EPH-ephrin mediated repulsion of cells, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • EPHA-mediated growth cone collapse, organism-specific biosystem (from REACTOME)
    EPHA-mediated growth cone collapse, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
    Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...

Markers

Homology

Clone Names

  • MGC129300, MGC129301

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ephrin receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
ephrin receptor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
 
ephrin receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
ephrin-A3
Names
EHK1 ligand
EPH-related receptor tyrosine kinase ligand 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010108.1NP_034238.1  ephrin-A3 precursor

    See identical proteins and their annotated locations for NP_034238.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125003
    Consensus CDS
    CCDS38488.1
    UniProtKB/Swiss-Prot
    O08545
    Related
    ENSMUSP00000029673, OTTMUSP00000036634, ENSMUST00000029673, OTTMUST00000071486
    Conserved Domains (1) summary
    cd10425
    Location:31158
    Ephrin-A_Ectodomain; Ectodomain of Ephrin A

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    89313899..89322960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500988.2XP_006501051.1  

    UniProtKB/TrEMBL
    A0A0G2JGE9
    Related
    ENSMUSP00000143539, OTTMUSP00000070432, ENSMUST00000200436, OTTMUST00000131893
    Conserved Domains (1) summary
    cd10425
    Location:31158
    Ephrin-A_Ectodomain; Ectodomain of Ephrin A

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    89350010..89357792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)