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Dpm1 dolichol-phosphate (beta-D) mannosyltransferase 1 [ Mus musculus (house mouse) ]

Gene ID: 13480, updated on 8-May-2016
Official Symbol
Dpm1provided by MGI
Official Full Name
dolichol-phosphate (beta-D) mannosyltransferase 1provided by MGI
Primary source
MGI:MGI:1330239
See related
Ensembl:ENSMUSG00000078919 Ensembl:ENSMUSG00000093752 Vega:OTTMUSG00000016047
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI118379; AI194292
Orthologs
Location:
2; 2 H3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (168209048..168230379, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (168034548..168055879, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33185 Neighboring gene activity-dependent neuroprotective protein Neighboring gene molybdenum cofactor synthesis 3 Neighboring gene potassium voltage-gated channel, subfamily G, member 1

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Readthrough Dpm1-adnp

Readthrough gene: Dpm1-adnp, Included gene: Adnp

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alcohol binding ISO
Inferred from Sequence Orthology
more info
 
dolichyl-phosphate beta-D-mannosyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
dolichyl-phosphate beta-D-mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
dolichyl-phosphate-mannose-protein mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
dolichyl-phosphate-mannose-protein mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
mannose binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
GDP-mannose metabolic process ISO
Inferred from Sequence Orthology
more info
 
GPI anchor biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
dolichol metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
dolichol metabolic process ISO
Inferred from Sequence Orthology
more info
 
protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
protein O-linked mannosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
protein O-linked mannosylation ISO
Inferred from Sequence Orthology
more info
 
protein mannosylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
dolichol-phosphate-mannose synthase complex ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
dolichol-phosphate mannosyltransferase subunit 1
Names
DPM synthase subunit 1
MPD synthase
dolichol-phosphate mannose synthase subunit 1
dolichyl-phosphate beta-D-mannosyltransferase subunit 1
mannose-P-dolichol synthase subunit 1
NP_034202.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310084.1NP_001297013.1  dolichol-phosphate mannosyltransferase subunit 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK004834, BF019794, BM941163, BX005039
    UniProtKB/Swiss-Prot
    O70152
    Conserved Domains (2) summary
    cd06442
    Location:29233
    DPM1_like; DPM1_like represents putative enzymes similar to eukaryotic DPM1
    COG0463
    Location:26198
    WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
  2. NM_010072.4NP_034202.1  dolichol-phosphate mannosyltransferase subunit 1 isoform 1

    See identical proteins and their annotated locations for NP_034202.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK005268, BM941163, BX005039
    Consensus CDS
    CCDS17109.1
    UniProtKB/Swiss-Prot
    O70152
    Related
    ENSMUSP00000118776, OTTMUSP00000017164, ENSMUST00000154111, OTTMUST00000038290
    Conserved Domains (2) summary
    cd06442
    Location:29256
    DPM1_like; DPM1_like represents putative enzymes similar to eukaryotic DPM1
    COG0463
    Location:26251
    WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    168209048..168230379 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    174153552..174174484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)