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Dpep1 dipeptidase 1 (renal) [ Mus musculus (house mouse) ]

Gene ID: 13479, updated on 8-May-2016
Official Symbol
Dpep1provided by MGI
Official Full Name
dipeptidase 1 (renal)provided by MGI
Primary source
MGI:MGI:94917
See related
Ensembl:ENSMUSG00000019278
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MBD; AI327012
Orthologs
Location:
8 E1; 8 72.08 cM
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 8 NC_000074.6 (123186235..123201812)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (125710135..125725712)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene sulfotransferase family 5A, member 1 Neighboring gene predicted gene, 42052 Neighboring gene ribosomal protein S12, pseudogene 9 Neighboring gene charged multivesicular body protein 1A Neighboring gene spermatogenesis associated 33

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
dipeptidase activity IEA
Inferred from Electronic Annotation
more info
 
dipeptidyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
metallodipeptidase activity ISO
Inferred from Sequence Orthology
more info
 
metalloexopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
modified amino acid binding ISO
Inferred from Sequence Orthology
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
antibiotic metabolic process ISO
Inferred from Sequence Orthology
more info
 
cellular response to drug ISO
Inferred from Sequence Orthology
more info
 
homocysteine metabolic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
apical part of cell ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
dipeptidase 1
Names
MBD-1
membrane bound dipeptidase type II
membrane-bound dipeptidase 1
microsomal dipeptidase
renal dipeptidase
NP_031902.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007876.2NP_031902.2  dipeptidase 1 precursor

    See identical proteins and their annotated locations for NP_031902.2

    Status: VALIDATED

    Source sequence(s)
    AI482156, AK002380, AK132644, BY229517, D13139
    Consensus CDS
    CCDS22750.1
    UniProtKB/Swiss-Prot
    P31428
    UniProtKB/TrEMBL
    Q3V175
    Related
    ENSMUSP00000019422, ENSMUST00000019422
    Conserved Domains (1) summary
    cd01301
    Location:31349
    rDP_like; renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p3 C57BL/6J

    Range
    123186235..123201812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000030.1 Alternate Mm_Celera

    Range
    127417731..127433354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)