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Dlg1 discs, large homolog 1 (Drosophila) [ Mus musculus (house mouse) ]

Gene ID: 13383, updated on 15-May-2016
Official Symbol
Dlg1provided by MGI
Official Full Name
discs, large homolog 1 (Drosophila)provided by MGI
Primary source
MGI:MGI:107231
See related
Ensembl:ENSMUSG00000022770 Vega:OTTMUSG00000016269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dlgh1; SAP97; SAP-97; mKIAA4187; E-dlg/SAP97; B130052P05Rik
Orthologs
Location:
16 B2; 16 22.4 cM
Exon count:
31
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (31663443..31873356)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (31664125..31873432)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34256 Neighboring gene predicted gene 536 Neighboring gene nucleoporin 37 pseudogene Neighboring gene antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 Neighboring gene predicted gene, 34476

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA4187

Gene Ontology Provided by MGI

Function Evidence Code Pubs
L27 domain binding ISO
Inferred from Sequence Orthology
more info
 
PDZ domain binding ISO
Inferred from Sequence Orthology
more info
 
guanylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
ionotropic glutamate receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
ionotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
kinase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
mitogen-activated protein kinase kinase binding ISO
Inferred from Sequence Orthology
more info
 
phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
potassium channel regulator activity ISO
Inferred from Sequence Orthology
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex scaffold IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
T cell activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
T cell cytokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
actin filament organization ISO
Inferred from Sequence Orthology
more info
 
activation of protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
amyloid precursor protein metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
astral microtubule organization ISO
Inferred from Sequence Orthology
more info
 
bicellular tight junction assembly ISO
Inferred from Sequence Orthology
more info
 
branching involved in ureteric bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular protein complex localization ISO
Inferred from Sequence Orthology
more info
 
cortical actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
cortical microtubule organization ISO
Inferred from Sequence Orthology
more info
 
embryonic skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
establishment of centrosome localization ISO
Inferred from Sequence Orthology
more info
 
establishment or maintenance of epithelial cell apical/basal polarity IBA
Inferred from Biological aspect of Ancestor
more info
 
hard palate development IMP
Inferred from Mutant Phenotype
more info
PubMed 
immunological synapse formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
lens development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane raft organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
negative regulation of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
negative regulation of p38MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein kinase B signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
peristalsis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of developmental growth TAS
Traceable Author Statement
more info
PubMed 
positive regulation of establishment of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
positive regulation of multicellular organism growth TAS
Traceable Author Statement
more info
PubMed 
positive regulation of potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
protein localization IGI
Inferred from Genetic Interaction
more info
PubMed 
protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
receptor clustering IBA
Inferred from Biological aspect of Ancestor
more info
 
receptor localization to synapse IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
regulation of membrane potential IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of membrane potential ISO
Inferred from Sequence Orthology
more info
 
regulation of myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein localization ISO
Inferred from Sequence Orthology
more info
 
reproductive structure development IMP
Inferred from Mutant Phenotype
more info
PubMed 
single organismal cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
smooth muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
 
tissue morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ureteric bud development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
MPP7-DLG1-LIN7 complex ISO
Inferred from Sequence Orthology
more info
 
T-tubule ISO
Inferred from Sequence Orthology
more info
 
basal lamina IDA
Inferred from Direct Assay
more info
PubMed 
basal plasma membrane ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane TAS
Traceable Author Statement
more info
PubMed 
bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cell junction ISO
Inferred from Sequence Orthology
more info
 
cell projection membrane IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell adherens junction TAS
Traceable Author Statement
more info
PubMed 
cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
immunological synapse IDA
Inferred from Direct Assay
more info
PubMed 
immunological synapse ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with ionotropic glutamate receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
lateral loop IDA
Inferred from Direct Assay
more info
PubMed 
lateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
microtubule ISO
Inferred from Sequence Orthology
more info
 
microvillus ISO
Inferred from Sequence Orthology
more info
 
myelin sheath abaxonal region IDA
Inferred from Direct Assay
more info
PubMed 
neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
node of Ranvier IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
paranode region of axon ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
presynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
disks large homolog 1
Names
embryo-dlg/synapse-associated protein 97

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252433.1NP_001239362.1  disks large homolog 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon and uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC129214, AY159380, BU058018
    UniProtKB/Swiss-Prot
    Q811D0
    Conserved Domains (7) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:705821
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:702880
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  2. NM_001252434.1NP_001239363.1  disks large homolog 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two exons and includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AC129214, AK143780, AY159380, BU058018
    Consensus CDS
    CCDS57026.1
    UniProtKB/Swiss-Prot
    Q811D0
    UniProtKB/TrEMBL
    H7BWY4, Q3UP61
    Related
    ENSMUSP00000023454, OTTMUSP00000017433, ENSMUST00000023454, OTTMUST00000039020
    Conserved Domains (7) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:684800
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:681859
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  3. NM_001252435.1NP_001239364.1  disks large homolog 1 isoform 4

    See identical proteins and their annotated locations for NP_001239364.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks an exon and includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
    Source sequence(s)
    AC126055, AC129214
    Consensus CDS
    CCDS57025.1
    UniProtKB/Swiss-Prot
    Q811D0
    Related
    ENSMUSP00000110859, OTTMUSP00000017431, ENSMUST00000115205, OTTMUST00000039018
    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:717833
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:714892
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  4. NM_001252436.1NP_001239365.1  disks large homolog 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and has multiple differences in the coding region, including the use of an alternate start codon, compared to variant 1. The encoded isoform (5) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC129214, AK142893, CF164686
    Consensus CDS
    CCDS57027.1
    UniProtKB/TrEMBL
    D3Z3B8
    Related
    ENSMUSP00000110850, OTTMUSP00000017435, ENSMUST00000115196, OTTMUST00000039022
    Conserved Domains (5) summary
    cd12031
    Location:499565
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:646762
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:643821
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:321382
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  5. NM_007862.3NP_031888.2  disks large homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_031888.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC129214, BC057118, BU058018
    Consensus CDS
    CCDS28107.1
    UniProtKB/Swiss-Prot
    Q811D0
    Related
    ENSMUSP00000064280, OTTMUSP00000017432, ENSMUST00000064477, OTTMUST00000039019
    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:739855
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:736914
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors

RNA

  1. NR_045516.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two exons, includes an alternate exon, and uses an alternate internal splice site, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC129214, AK220189, BU058018
    Related
    ENSMUST00000132176, OTTMUST00000039017

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    31663443..31873356
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521761.2XP_006521824.1  

    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:751867
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:748926
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  2. XM_006521763.2XP_006521826.1  

    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:746862
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:743921
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  3. XM_006521762.2XP_006521825.1  

    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:750866
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:747925
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  4. XM_006521765.2XP_006521828.1  

    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:729845
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:726904
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  5. XM_006521766.2XP_006521829.1  

    UniProtKB/TrEMBL
    E9Q9H0
    Related
    ENSMUSP00000110855, OTTMUSP00000017436, ENSMUST00000115201, OTTMUST00000039023
    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:724840
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:721899
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  6. XM_006521768.2XP_006521831.1  

    See identical proteins and their annotated locations for XP_006521831.1

    UniProtKB/Swiss-Prot
    Q811D0
    Related
    ENSMUSP00000097581, ENSMUST00000100001
    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:717833
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:714892
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  7. XM_006521764.2XP_006521827.1  

    Conserved Domains (8) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:567633
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:736852
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:733911
    Guanylate_kin; Guanylate kinase
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:406450
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  8. XM_006521767.2XP_006521830.1  

    Conserved Domains (7) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:718834
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:715893
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  9. XM_011245823.1XP_011244125.1  

    Conserved Domains (6) summary
    pfam09058
    Location:264
    L27_1; L27_1
    pfam10608
    Location:106128
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam06583
    Location:74231
    Neogenin_C; Neogenin C-terminus
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  10. XM_006521770.2XP_006521833.1  

    Conserved Domains (6) summary
    pfam10608
    Location:1032
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    cd12031
    Location:486552
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:655771
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:128212
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:652830
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:308369
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  11. XM_006521769.1XP_006521832.1  

    Conserved Domains (5) summary
    cd12031
    Location:499565
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:668784
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:665843
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:321382
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  12. XM_006521771.1XP_006521834.1  

    Conserved Domains (5) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:635751
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:632810
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  13. XM_006521772.1XP_006521835.1  

    Conserved Domains (5) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:613729
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:610788
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  14. XM_006521773.1XP_006521836.1  

    Conserved Domains (5) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    cd00071
    Location:601717
    GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:598776
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors

RNA

  1. XR_384523.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    32161016..32367224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)