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Dck deoxycytidine kinase [ Mus musculus (house mouse) ]

Gene ID: 13178, updated on 21-May-2016
Official Symbol
Dckprovided by MGI
Official Full Name
deoxycytidine kinaseprovided by MGI
Primary source
MGI:MGI:102726
See related
Ensembl:ENSMUSG00000029366 Vega:OTTMUSG00000025239
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
Location:
5; 5 E2
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (88765013..88783277)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (89194038..89212302)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene G-rich RNA sequence binding factor 1 Neighboring gene MOB kinase activator 1B Neighboring gene makorin, ring finger protein 1, pseudogene 1 Neighboring gene solute carrier family 4 (anion exchanger), member 4 Neighboring gene predicted gene, 35855

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding ISO
Inferred from Sequence Orthology
more info
 
deoxycytidine kinase activity ISO
Inferred from Sequence Orthology
more info
 
drug binding ISO
Inferred from Sequence Orthology
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
nucleoside kinase activity ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
pyrimidine deoxyribonucleoside binding ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
deoxycytidine metabolic process ISO
Inferred from Sequence Orthology
more info
 
deoxyribonucleoside monophosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
drug metabolic process ISO
Inferred from Sequence Orthology
more info
 
nucleobase-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
pyrimidine nucleotide metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
deoxycytidine kinase
NP_031858.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007832.4NP_031858.1  deoxycytidine kinase

    See identical proteins and their annotated locations for NP_031858.1

    Status: VALIDATED

    Source sequence(s)
    BC060062, BU052737
    Consensus CDS
    CCDS19405.1
    UniProtKB/Swiss-Prot
    P43346
    UniProtKB/TrEMBL
    Q545E8
    Related
    ENSMUSP00000031311, OTTMUSP00000030586, ENSMUST00000031311, OTTMUST00000062134
    Conserved Domains (2) summary
    COG1428
    Location:24260
    Dck; Deoxyadenosine/deoxycytidine kinase [Nucleotide transport and metabolism]
    cd01673
    Location:23244
    dNK; Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    88765013..88783277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    86914328..86932500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)