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TBXG_003746 ATP-dependent DNA ligase ligC [ Mycobacterium tuberculosis KZN 605 ]

Gene ID: 13159628, updated on 6-Jul-2014
Gene symbol
TBXG_003746
Gene description
ATP-dependent DNA ligase ligC
Locus tag
TBXG_003746
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis KZN 605 (strain: KZN 605, nat-host: Homo sapiens, other: extensively drug resistant)
Lineage
Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Sequence:
NC_018078.1 (4169573..4170649)

NC_018078.1Genomic Context describing neighboring genes Neighboring gene transferase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Base excision repair, organism-specific biosystem (from KEGG)
    Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
  • Base excision repair, conserved biosystem (from KEGG)
    Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
  • Mismatch repair, organism-specific biosystem (from KEGG)
    Mismatch repair, organism-specific biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
  • Mismatch repair, conserved biosystem (from KEGG)
    Mismatch repair, conserved biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
  • Non-homologous end-joining, organism-specific biosystem (from KEGG)
    Non-homologous end-joining, organism-specific biosystemNonhomologous end joining (NHEJ) eliminates DNA double-strand breaks (DSBs) by direct ligation. NHEJ involves binding of the KU heterodimer to double-stranded DNA ends, recruitment of DNA-PKcs (MRX c...
  • Non-homologous end-joining, conserved biosystem (from KEGG)
    Non-homologous end-joining, conserved biosystemNonhomologous end joining (NHEJ) eliminates DNA double-strand breaks (DSBs) by direct ligation. NHEJ involves binding of the KU heterodimer to double-stranded DNA ends, recruitment of DNA-PKcs (MRX c...
  • Nucleotide excision repair, organism-specific biosystem (from KEGG)
    Nucleotide excision repair, organism-specific biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...
  • Nucleotide excision repair, conserved biosystem (from KEGG)
    Nucleotide excision repair, conserved biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_018078.1 

    Range
    4169573..4170649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_006475258.1 ATP-dependent DNA ligase ligC [Mycobacterium tuberculosis KZN 605]

    See proteins identical to YP_006475258.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    I6RL71
    Conserved Domains (3) summary
    cd07970
    Location:204339
    OBF_DNA_ligase_LigC; The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigC is a DNA-binding module that is part of the catalytic core unit
    cd07905
    Location:9204
    Adenylation_DNA_ligase_LigC; Adenylation domain of Mycobacterium tuberculosis LigC-like ATP-dependent DNA ligases
    PRK08224
    Location:1358
    ligC; ATP-dependent DNA ligase; Reviewed