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Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 [ Mus musculus (house mouse) ]

Gene ID: 13072, updated on 28-May-2016
Official Symbol
Cyp11b2provided by MGI
Official Full Name
cytochrome P450, family 11, subfamily b, polypeptide 2provided by MGI
Primary source
MGI:MGI:88584
See related
Ensembl:ENSMUSG00000022589 Vega:OTTMUSG00000035251
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cpn2; Cyp11b; Cyp11b-2
Location:
15 D3; 15 34.29 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (74851010..74856318, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (74681440..74686748, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene glycosylphosphatidylinositol anchored molecule like Neighboring gene glycosylphosphatidylinositol anchored molecule like 2 Neighboring gene cytochrome P450, family 11, subfamily b, polypeptide 1 Neighboring gene predicted gene, 41347 Neighboring gene RIKEN cDNA 2010109I03 gene Neighboring gene predicted gene 6610

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC151285

Gene Ontology Provided by MGI

Function Evidence Code Pubs
corticosterone 18-monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
corticosterone 18-monooxygenase activity ISO
Inferred from Sequence Orthology
more info
 
heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IBA
Inferred from Biological aspect of Ancestor
more info
 
steroid 11-beta-monooxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
steroid 11-beta-monooxygenase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
C21-steroid hormone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
aldosterone biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
aldosterone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
cellular response to peptide hormone stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
cholesterol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
cortisol biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
cortisol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
drinking behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucocorticoid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
glucocorticoid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of blood pressure ISO
Inferred from Sequence Orthology
more info
 
regulation of blood pressure ISO
Inferred from Sequence Orthology
more info
 
regulation of blood volume by renal aldosterone IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of systemic arterial blood pressure by circulatory renin-angiotensin IMP
Inferred from Mutant Phenotype
more info
PubMed 
secondary metabolite biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
steroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
dendrite ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cytochrome P450 11B2, mitochondrial
Names
CYPXIB2
aldosterone synthase
cytochrome P450C11
steroid 11-beta-hydroxylase
steroid-11-beta-hydroxylase
NP_034121.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009991.3NP_034121.3  cytochrome P450 11B2, mitochondrial

    See identical proteins and their annotated locations for NP_034121.3

    Status: VALIDATED

    Source sequence(s)
    BC119321
    Consensus CDS
    CCDS27536.2
    UniProtKB/Swiss-Prot
    P15539
    UniProtKB/TrEMBL
    G3UWE4
    Related
    ENSMUSP00000131503, OTTMUSP00000049180, ENSMUST00000167634, OTTMUST00000089902
    Conserved Domains (1) summary
    pfam00067
    Location:44498
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    74851010..74856318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    76357529..76362843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)