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Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 [ Mus musculus (house mouse) ]

Gene ID: 13002, updated on 8-May-2016
Official Symbol
Dnajc5provided by MGI
Official Full Name
DnaJ heat shock protein family (Hsp40) member C5provided by MGI
Primary source
MGI:MGI:892995
See related
Ensembl:ENSMUSG00000000826 Vega:OTTMUSG00000016739
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Csp; AU018536; 2610314I24Rik
Orthologs
Location:
2 H4; 2 103.63 cM
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (181520305..181552886)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (181255210..181286954)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 16B Neighboring gene tumor protein D52-like 2 Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand Neighboring gene zinc finger protein 512B Neighboring gene microRNA 7006

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
glycoprotein binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
negative regulation of neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
dnaJ homolog subfamily C member 5
Names
DnaJ (Hsp40) homolog, subfamily C, member 5
cysteine string protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271584.1NP_001258513.1  dnaJ homolog subfamily C member 5

    See identical proteins and their annotated locations for NP_001258513.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' UTR and contains another compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AK029006, AK035288, BY101584, BY333630
    Consensus CDS
    CCDS17215.1
    UniProtKB/Swiss-Prot
    P60904
    Related
    ENSMUSP00000104425, OTTMUSP00000018140, ENSMUST00000108797, OTTMUST00000040587
    Conserved Domains (2) summary
    cd06257
    Location:1769
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    COG0484
    Location:1584
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
  2. NM_001271585.1NP_001258514.1  dnaJ homolog subfamily C member 5

    See identical proteins and their annotated locations for NP_001258514.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AK029006, AK035288, BY333630, CB249513
    Consensus CDS
    CCDS17215.1
    UniProtKB/Swiss-Prot
    P60904
    Conserved Domains (2) summary
    cd06257
    Location:1769
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    COG0484
    Location:1584
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
  3. NM_016775.3NP_058055.1  dnaJ homolog subfamily C member 5

    See identical proteins and their annotated locations for NP_058055.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
    Source sequence(s)
    AK029006, AK035288, BY333630
    Consensus CDS
    CCDS17215.1
    UniProtKB/Swiss-Prot
    P60904
    Related
    ENSMUSP00000072175, OTTMUSP00000018139, ENSMUST00000072334, OTTMUST00000040585
    Conserved Domains (2) summary
    cd06257
    Location:1769
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    COG0484
    Location:1584
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

RNA

  1. NR_073369.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an exon in the 5' end and contains an alternate exon in the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK029006, AK035288, BY333630, CN459638
    Related
    ENSMUST00000116365, OTTMUST00000040586

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    181520305..181552886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239923.1XP_011238225.1  

    See identical proteins and their annotated locations for XP_011238225.1

    UniProtKB/Swiss-Prot
    P60904
    Related
    ENSMUSP00000104424, OTTMUSP00000018141, ENSMUST00000108796, OTTMUST00000040588
    Conserved Domains (2) summary
    cd06257
    Location:1769
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    COG0484
    Location:1584
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
  2. XM_011239924.1XP_011238226.1  

    See identical proteins and their annotated locations for XP_011238226.1

    UniProtKB/Swiss-Prot
    P60904
    Conserved Domains (2) summary
    cd06257
    Location:1769
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    COG0484
    Location:1584
    DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

RNA

  1. XR_867108.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    185601929..185634351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)