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Col4a3 collagen, type IV, alpha 3 [ Mus musculus (house mouse) ]

Gene ID: 12828, updated on 28-May-2016
Official Symbol
Col4a3provided by MGI
Official Full Name
collagen, type IV, alpha 3provided by MGI
Primary source
MGI:MGI:104688
See related
Ensembl:ENSMUSG00000079465 Vega:OTTMUSG00000021696
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
[a]3(IV); alpha3(IV)
Orthologs
Location:
1; 1 C5
Exon count:
52
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (82586921..82722059)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (82583496..82718634)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34227 Neighboring gene rhomboid domain containing 1 Neighboring gene collagen, type IV, alpha 4 Neighboring gene uncharacterized LOC105243964 Neighboring gene uncharacterized LOC105243963 Neighboring gene predicted gene, 39668 Neighboring gene mitochondrial fission factor Neighboring gene transmembrane 4 L six family member 20

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 
integrin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell proliferation ISO
Inferred from Sequence Orthology
more info
 
cell surface receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
collagen-activated tyrosine kinase receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
endothelial cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
glomerular basement membrane development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of angiogenesis IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
basement membrane IDA
Inferred from Direct Assay
more info
PubMed 
basement membrane ISO
Inferred from Sequence Orthology
more info
 
collagen trimer IEA
Inferred from Electronic Annotation
more info
 
collagen type IV trimer IDA
Inferred from Direct Assay
more info
PubMed 
collagen type IV trimer ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
proteinaceous extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
collagen alpha-3(IV) chain
Names
col4a3
collagen type IV alpha3 chain
procollagen, type IV, alpha 3
tumstatin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007734.2NP_031760.2  collagen alpha-3(IV) chain precursor

    See identical proteins and their annotated locations for NP_031760.2

    Status: VALIDATED

    Source sequence(s)
    AC138214, AF169387, BB605811
    Consensus CDS
    CCDS35631.1
    UniProtKB/Swiss-Prot
    Q9QZS0
    Related
    ENSMUSP00000109084, OTTMUSP00000024235, ENSMUST00000113457, OTTMUST00000051474
    Conserved Domains (3) summary
    smart00111
    Location:15541666
    C4; C-terminal tandem repeated domain in type 4 procollagens
    pfam01413
    Location:14441553
    C4; C-terminal tandem repeated domain in type 4 procollagen
    pfam01391
    Location:13771436
    Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    82586921..82722059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    82656003..82788458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)