U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC1279886 E3 ubiquitin-protein ligase CHIP [ Anopheles gambiae (African malaria mosquito) ]

Gene ID: 1279886, updated on 4-Jan-2024

Summary

Go to the top of the page Help
Gene symbol
LOC1279886
Gene description
E3 ubiquitin-protein ligase CHIP
Gene type
protein coding
RefSeq status
MODEL
Organism
Anopheles gambiae
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 3 NC_064602.1 (20436555..20441113)

Chromosome 3 - NC_064602.1Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase 2 Neighboring gene MAPK regulated corepressor interacting protein 2 Neighboring gene uncharacterized LOC133393413 Neighboring gene uncharacterized LOC1279888 Neighboring gene uncharacterized LOC133394051

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_064602.1 Chromosome 3 Reference idAnoGambNW_F1_1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Anopheles gambiae genome: an update. Mongin E, et al. Trends Parasitol, 2004 Feb. PMID 14747013
  2. The genome sequence of the malaria mosquito Anopheles gambiae. Holt RA, et al. Science, 2002 Oct 4. PMID 12364791

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to misfolded protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
E3 ubiquitin-protein ligase CHIP

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference idAnoGambNW_F1_1 Primary Assembly

Genomic

  1. NC_064602.1 Reference idAnoGambNW_F1_1 Primary Assembly

    Range
    20436555..20441113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_319666.5 → XP_319666.2  E3 ubiquitin-protein ligase CHIP

    See identical proteins and their annotated locations for XP_319666.2

    UniProtKB/TrEMBL
    Q7PWM1
    Conserved Domains (4) summary
    PLN03088
    Location:15 → 113
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    sd00006
    Location:16 → 41
    TPR; TPR repeat [structural motif]
    cd16654
    Location:212 → 278
    RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
    pfam18391
    Location:129 → 210
    CHIP_TPR_N; CHIP N-terminal tetratricopeptide repeat domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials