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Ackr3 atypical chemokine receptor 3 [ Mus musculus (house mouse) ]

Gene ID: 12778, updated on 3-May-2016
Official Symbol
Ackr3provided by MGI
Official Full Name
atypical chemokine receptor 3provided by MGI
Primary source
MGI:MGI:109562
See related
Ensembl:ENSMUSG00000044337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rdc1; Cxcr7; RDC-1; CXC-R7; CXCR-7; Cmkor1; AW541270
Orthologs
Location:
1 D; 1 45.28 cM
Exon count:
3
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (90203980..90215724)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (92100578..92112863)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene IQ motif containing with AAA domain Neighboring gene RIKEN cDNA 4930434B07 gene Neighboring gene predicted gene, 34930 Neighboring gene uncharacterized LOC102638195 Neighboring gene predicted gene, 41916

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
C-X-C chemokine binding ISO
Inferred from Sequence Orthology
more info
 
C-X-C chemokine receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
chemokine binding IEA
Inferred from Electronic Annotation
more info
 
coreceptor activity IEA
Inferred from Electronic Annotation
more info
 
scavenger receptor activity ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
chemokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemotaxis IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of defense response to virus by host ISO
Inferred from Sequence Orthology
more info
 
receptor internalization ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
vasculogenesis IEA
Inferred from Electronic Annotation
more info
 
xenophagy ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
coated pit ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
atypical chemokine receptor 3
Names
C-X-C chemokine receptor type 7
G-protein coupled receptor RDC1 homolog
chemokine (C-X-C motif) receptor 7
chemokine orphan receptor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271607.1NP_001258536.1  atypical chemokine receptor 3

    See identical proteins and their annotated locations for NP_001258536.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC110261, AC120878
    Consensus CDS
    CCDS15152.1
    UniProtKB/Swiss-Prot
    P56485
    Conserved Domains (1) summary
    pfam00001
    Location:67315
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_007722.4NP_031748.2  atypical chemokine receptor 3

    See identical proteins and their annotated locations for NP_031748.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC110261, AK031100, BQ033958
    Consensus CDS
    CCDS15152.1
    UniProtKB/Swiss-Prot
    P56485
    Related
    ENSMUSP00000069114, OTTMUSP00000037197, ENSMUST00000065587, OTTMUST00000072324
    Conserved Domains (1) summary
    pfam00001
    Location:67315
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    90203980..90215724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    93147370..93159118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)