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Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 [ Mus musculus (house mouse) ]

Gene ID: 12705, updated on 28-May-2016
Official Symbol
Cited1provided by MGI
Official Full Name
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1provided by MGI
Primary source
MGI:MGI:108023
See related
Ensembl:ENSMUSG00000051159 Vega:OTTMUSG00000018307
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Msg1; AI316840; AU019144
Orthologs
Location:
X D; X 45.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (102247378..102252181, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (99442775..99447108, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S4, X-linked Neighboring gene predicted gene 14859 Neighboring gene predicted gene 14858 Neighboring gene histone deacetylase 8 Neighboring gene predicted gene, 32262

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
LBD domain binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
co-SMAD binding ISO
Inferred from Sequence Orthology
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, sequence-specific DNA binding NAS
Non-traceable Author Statement
more info
PubMed 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
SMAD protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
NOT branching involved in ureteric bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
embryonic axis specification ISO
Inferred from Sequence Orthology
more info
 
NOT kidney development IMP
Inferred from Mutant Phenotype
more info
PubMed 
labyrinthine layer development IMP
Inferred from Mutant Phenotype
more info
PubMed 
melanin biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
melanocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
melanocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
NOT morphogenesis of an epithelium IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of osteoblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
nucleocytoplasmic transport ISO
Inferred from Sequence Orthology
more info
 
pigmentation IDA
Inferred from Direct Assay
more info
PubMed 
pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
pigmentation ISO
Inferred from Sequence Orthology
more info
 
placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to cAMP IDA
Inferred from Direct Assay
more info
PubMed 
response to cytokine IDA
Inferred from Direct Assay
more info
PubMed 
response to estrogen ISO
Inferred from Sequence Orthology
more info
 
response to insulin IDA
Inferred from Direct Assay
more info
PubMed 
response to interferon-gamma IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-1 IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-11 IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-2 IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-4 IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-6 IDA
Inferred from Direct Assay
more info
PubMed 
response to interleukin-9 IDA
Inferred from Direct Assay
more info
PubMed 
response to lipopolysaccharide IDA
Inferred from Direct Assay
more info
PubMed 
response to parathyroid hormone IDA
Inferred from Direct Assay
more info
PubMed 
response to transforming growth factor beta ISO
Inferred from Sequence Orthology
more info
 
spongiotrophoblast layer development IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cbp/p300-interacting transactivator 1
Names
melanocyte-specific protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276466.1NP_001263395.1  cbp/p300-interacting transactivator 1 isoform a

    See identical proteins and their annotated locations for NP_001263395.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AK148042, AL954850
    Consensus CDS
    CCDS30322.1
    UniProtKB/Swiss-Prot
    P97769
    UniProtKB/TrEMBL
    Q3UGA1
    Related
    ENSMUSP00000051789, OTTMUSP00000019880, ENSMUST00000050551, OTTMUST00000044231
    Conserved Domains (1) summary
    pfam04487
    Location:1201
    CITED; CITED
  2. NM_001276473.1NP_001263402.1  cbp/p300-interacting transactivator 1 isoform a

    See identical proteins and their annotated locations for NP_001263402.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AK148042, AL954850
    Consensus CDS
    CCDS30322.1
    UniProtKB/Swiss-Prot
    P97769
    UniProtKB/TrEMBL
    Q3UGA1
    Conserved Domains (1) summary
    pfam04487
    Location:1201
    CITED; CITED
  3. NM_001276474.1NP_001263403.1  cbp/p300-interacting transactivator 1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a.
    Source sequence(s)
    AK148042, AL954850, BC052030, CX237826
    UniProtKB/Swiss-Prot
    P97769
    UniProtKB/TrEMBL
    Q3UGA1
    Conserved Domains (1) summary
    pfam04487
    Location:29229
    CITED; CITED
  4. NM_007709.4NP_031735.1  cbp/p300-interacting transactivator 1 isoform a

    See identical proteins and their annotated locations for NP_031735.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same isoform (a).
    Source sequence(s)
    AL954850, BC052030, BQ173936
    Consensus CDS
    CCDS30322.1
    UniProtKB/Swiss-Prot
    P97769
    UniProtKB/TrEMBL
    Q3UGA1
    Related
    ENSMUSP00000098890, OTTMUSP00000019881, ENSMUST00000101336, OTTMUST00000044232
    Conserved Domains (1) summary
    pfam04487
    Location:1201
    CITED; CITED

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    102247378..102252181 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    89158465..89163268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)