Format

Send to:

Choose Destination

Cdc25a cell division cycle 25A [ Mus musculus (house mouse) ]

Gene ID: 12530, updated on 28-May-2016
Official Symbol
Cdc25aprovided by MGI
Official Full Name
cell division cycle 25Aprovided by MGI
Primary source
MGI:MGI:103198
See related
Ensembl:ENSMUSG00000032477 Vega:OTTMUSG00000051511
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D9Ertd393e
Orthologs
Location:
9 F2; 9 59.81 cM
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (109875337..109893895)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (109778083..109796394)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene cathelicidin antimicrobial peptide Neighboring gene predicted gene, 39427 Neighboring gene microRNA 7089 Neighboring gene ribosomal protein L32 pseudogene Neighboring gene microtubule-associated protein 4 Neighboring gene 60S ribosomal protein L7 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoprotein phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cellular response to UV ISO
Inferred from Sequence Orthology
more info
 
mitotic M phase IEA
Inferred from Electronic Annotation
more info
 
mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
response to radiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intracellular IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
M-phase inducer phosphatase 1
Names
dual specificity phosphatase Cdc25A
NP_031684.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007658.3NP_031684.3  M-phase inducer phosphatase 1

    See identical proteins and their annotated locations for NP_031684.3

    Status: VALIDATED

    Source sequence(s)
    AK077609, AK077991, BE854932, BU700379
    Consensus CDS
    CCDS23559.1
    UniProtKB/Swiss-Prot
    P48964
    Related
    ENSMUSP00000091882, OTTMUSP00000069797, ENSMUST00000094324, OTTMUST00000130111
    Conserved Domains (2) summary
    cd01530
    Location:347464
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85319
    M-inducer_phosp; M-phase inducer phosphatase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    109875337..109893895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511930.2XP_006511993.1  

    Conserved Domains (2) summary
    cd01530
    Location:354471
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85326
    M-inducer_phosp; M-phase inducer phosphatase
  2. XM_006511929.2XP_006511992.1  

    Conserved Domains (2) summary
    cd01530
    Location:355472
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85327
    M-inducer_phosp; M-phase inducer phosphatase
  3. XM_006511931.2XP_006511994.1  

    Conserved Domains (2) summary
    cd01530
    Location:346463
    Cdc25; Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to ...
    pfam06617
    Location:85318
    M-inducer_phosp; M-phase inducer phosphatase

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    109601935..109621511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)