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    Cd36 CD36 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12491, updated on 11-May-2013
    Official Symbol
    Cd36provided by MGI
    Official Full Name
    CD36 antigenprovided by MGI
    Primary source
    MGI:107899
    See related
    Ensembl:ENSMUSG00000002944
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FAT; GPIV; Scarb3
    Location :
    5 A3; 5 8.11 cM
    Sequence :
    Chromosome: 5; NC_000071.6 (17781690..17888959, complement)
    See Cd36 in Epigenomics, MapViewer

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C Neighboring gene microRNA 5109 Neighboring gene guanine nucleotide binding protein, alpha transducing 3 Neighboring gene guanine nucleotide binding protein (G protein), alpha inhibiting 1 Neighboring gene predicted gene 3527

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:198587 BioGRID:200268 Htt    BioGRID  PubMed Affinity Capture-MS 

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Gram-negative bacterial cell surface binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Gram-positive bacterial cell surface binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    high-density lipoprotein particle binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    lipoprotein particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipoteichoic acid receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    low-density lipoprotein particle binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    low-density lipoprotein particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    low-density lipoprotein receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    oleic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    thrombospondin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transforming growth factor beta binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    apoptotic cell clearance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cGMP-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
     
    cellular response to bacterial lipopeptide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to hydroperoxide IMP
    Inferred from Mutant Phenotype
    more info
     
    cellular response to lipopolysaccharide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to lipoteichoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to lipoteichoic acid IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cholesterol transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    defense response to Gram-positive bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    lipid storage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lipid storage ISO
    Inferred from Sequence Orthology
    more info
     
    lipoprotein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lipoprotein transport ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid import ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle clearance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    low-density lipoprotein particle clearance ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle mediated signaling IDA
    Inferred from Direct Assay
    more info
     
    negative regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
     
    negative regulation of growth of symbiont in host IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of systemic arterial blood pressure ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription factor import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
     
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
     
    nitric oxide mediated signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    pattern recognition receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phagocytosis, recognition IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma lipoprotein particle clearance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasma membrane long-chain fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of I-kappaB kinase/NF-kappaB cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of blood coagulation IMP
    Inferred from Mutant Phenotype
    more info
     
    positive regulation of blood microparticle formation IMP
    Inferred from Mutant Phenotype
    more info
     
    positive regulation of cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cholesterol storage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cytokine secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of interleukin-12 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of interleukin-6 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of macrophage cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of macrophage derived foam cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of macrophage derived foam cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-tyrosine phosphorylation IDA
    Inferred from Direct Assay
    more info
     
    positive regulation of phagocytosis, engulfment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
     
    positive regulation of tumor necrosis factor production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of removal of superoxide radicals IMP
    Inferred from Mutant Phenotype
    more info
     
    regulation of transcription from RNA polymerase II promoter in response to oxidative stress IC
    Inferred by Curator
    more info
     
    response to mechanical stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    triglyceride metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    caveola ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    sarcolemma ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    platelet glycoprotein 4
    Names
    platelet glycoprotein 4
    PAS-4
    GPIIIB
    PAS IV
    glycoprotein IIIb
    fatty acid translocase
    platelet glycoprotein IV

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159555.1NP_001153027.1  platelet glycoprotein 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 4, and 5 encode the same protein.
      Source sequence(s)
      AK052825, AK151355, AW261674, AW986994, BB534670
      Consensus CDS
      CCDS19100.1
      UniProtKB/Swiss-Prot
      Q08857
      UniProtKB/TrEMBL
      Q3UAI3
      UniProtKB/TrEMBL
      Q8C6Z4
      Related
      ENSMUSP00000080974, ENSMUST00000082367
      Conserved Domains (1) summary
      pfam01130
      Location:26464
      Blast Score: 1286
      CD36; CD36 family
    2. NM_001159556.1NP_001153028.1  platelet glycoprotein 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 4, and 5 encode the same protein.
      Source sequence(s)
      AK052825, AK150648, AW261674, BB534670, BY126014
      Consensus CDS
      CCDS19100.1
      UniProtKB/Swiss-Prot
      Q08857
      UniProtKB/TrEMBL
      Q3UAI3
      UniProtKB/TrEMBL
      Q3UC79
      UniProtKB/TrEMBL
      Q8C6Z4
      Related
      ENSMUSP00000133008, ENSMUST00000170051
      Conserved Domains (1) summary
      pfam01130
      Location:26464
      Blast Score: 1286
      CD36; CD36 family
    3. NM_001159557.1NP_001153029.1  platelet glycoprotein 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 4, and 5 encode the same protein.
      Source sequence(s)
      AK052825, AK128908, AK150648, AK151355, AW261674, BB534670, BY126014
      Consensus CDS
      CCDS19100.1
      UniProtKB/Swiss-Prot
      Q08857
      UniProtKB/TrEMBL
      Q3UAI3
      UniProtKB/TrEMBL
      Q3UC79
      UniProtKB/TrEMBL
      Q8C6Z4
      Related
      ENSMUSP00000126300, ENSMUST00000165232
      Conserved Domains (1) summary
      pfam01130
      Location:26464
      Blast Score: 1286
      CD36; CD36 family
    4. NM_001159558.1NP_001153030.1  platelet glycoprotein 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AK052825, AK128908, AW261674, BB534670, BQ926044
      Consensus CDS
      CCDS19100.1
      UniProtKB/Swiss-Prot
      Q08857
      UniProtKB/TrEMBL
      Q3UAI3
      UniProtKB/TrEMBL
      Q8C6Z4
      Related
      ENSMUSP00000131832, ENSMUST00000169095
      Conserved Domains (1) summary
      pfam01130
      Location:26464
      Blast Score: 1286
      CD36; CD36 family
    5. NM_007643.4NP_031669.3  platelet glycoprotein 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 4, and 5 encode the same protein.
      Source sequence(s)
      AK052825, AK152904, AW261674, AW986994, BB534670
      Consensus CDS
      CCDS19100.1
      UniProtKB/Swiss-Prot
      Q08857
      UniProtKB/TrEMBL
      Q3U6Y9
      UniProtKB/TrEMBL
      Q3UAI3
      UniProtKB/TrEMBL
      Q8C6Z4
      Conserved Domains (1) summary
      pfam01130
      Location:26464
      Blast Score: 1286
      CD36; CD36 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p1 C57BL/6J

      Range
      17781690..17888959, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000027.1 Alternate Mm_Celera

      Range
      14757802..14864361, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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