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Rb1cc1 RB1-inducible coiled-coil 1 [ Mus musculus (house mouse) ]

Gene ID: 12421, updated on 28-May-2016
Official Symbol
Rb1cc1provided by MGI
Official Full Name
RB1-inducible coiled-coil 1provided by MGI
Primary source
MGI:MGI:1341850
See related
Ensembl:ENSMUSG00000025907 Vega:OTTMUSG00000033467
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cc1; FIP200; LaXp180; 2900055E04Rik; 5930404L04Rik
Orthologs
Location:
1; 1 A2
Exon count:
27
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (6214642..6276372)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (6204743..6266185)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene COP9 (constitutive photomorphogenic) homolog, subunit 2 pseudogene Neighboring gene RIKEN cDNA 4732440D04 gene Neighboring gene uncharacterized protein C9orf40 homolog pseudogene Neighboring gene family with sequence similarity 150, member A Neighboring gene motile sperm domain containing 1 pseudogene Neighboring gene calmodulin regulated spectrin-associated protein 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
autophagosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagy IEA
Inferred from Electronic Annotation
more info
 
autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
liver development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of JNK cascade IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell size IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
ATG1/ULK1 kinase complex IDA
Inferred from Direct Assay
more info
PubMed 
ATG1/ULK1 kinase complex IPI
Inferred from Physical Interaction
more info
PubMed 
ATG1/ULK1 kinase complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
pre-autophagosomal structure IDA
Inferred from Direct Assay
more info
PubMed 
pre-autophagosomal structure membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
RB1-inducible coiled-coil protein 1
Names
200 kDa FAK family kinase-interacting protein
FAK family kinase-interacting protein of 200 kDa
coiled coil forming protein 1
coiled-coil-forming protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009826.4NP_033956.2  RB1-inducible coiled-coil protein 1

    See identical proteins and their annotated locations for NP_033956.2

    Status: VALIDATED

    Source sequence(s)
    AB070619, AK033709, AK041038, CN720888
    Consensus CDS
    CCDS35507.1
    UniProtKB/Swiss-Prot
    Q9ESK9
    Related
    ENSMUSP00000027040, OTTMUSP00000045266, ENSMUST00000027040, OTTMUST00000084091
    Conserved Domains (5) summary
    pfam10377
    Location:14561584
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl12013
    Location:8641069
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    6214642..6276372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238339.1XP_011236641.1  

    See identical proteins and their annotated locations for XP_011236641.1

    Conserved Domains (5) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10377
    Location:15061602
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)
  2. XM_011238340.1XP_011236642.1  

    See identical proteins and their annotated locations for XP_011236642.1

    Conserved Domains (5) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10377
    Location:15061602
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)
  3. XM_011238338.1XP_011236640.1  

    See identical proteins and their annotated locations for XP_011236640.1

    Conserved Domains (5) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10377
    Location:15061602
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)
  4. XM_011238341.1XP_011236643.1  

    Conserved Domains (5) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10377
    Location:15061599
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)
  5. XM_006495443.2XP_006495506.1  

    Conserved Domains (5) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10377
    Location:14561581
    ATG11; Autophagy-related protein 11
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)
  6. XM_011238342.1XP_011236644.1  

    Conserved Domains (4) summary
    COG0419
    Location:8421373
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cl03951
    Location:10761195
    CDC37_N; Cdc37 N terminal kinase binding
    cl00155
    Location:377
    UBQ; Ubiquitin-like proteins
    cl21485
    Location:11781269
    OmpH; Outer membrane protein (OmpH-like)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    6202698..6263115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)