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    IQCK IQ motif containing K [ Homo sapiens ]

    Gene ID: 124152, updated on 11-May-2012
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    Summary

    Official Symbol
    IQCKprovided by HGNC
    Official Full Name
    IQ motif containing Kprovided by HGNC
    Primary source
    HGNC:28556
    See related
    Ensembl:ENSG00000174628; HPRD:11340; Vega:OTTHUMG00000131453
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FLJ20115; FLJ36575; MGC35048
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    Genomic context

    Location :
    16p12.3
    Sequence :
    Chromosome: 16; NC_000016.9 (19727778..19868861)
    See IQCK in Epigenomics, MapViewer

    Chromosome 16 - NC_000016.9Genomic Context describing neighboring genes Neighboring gene centriolar coiled coil protein 110kDa Neighboring gene chromosome 16 open reading frame 62 Neighboring gene chromosome 16 open reading frame 88 Neighboring gene G protein-coupled receptor, family C, group 5, member B Neighboring gene G protein-coupled receptor 139

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Li C, et al. Oncogene, 2011 Oct 20. PMID 21577200.
    2. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Speliotes EK, et al. Nat Genet, 2010 Nov. PMID 20935630.
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. Bailey SD, et al. Diabetes Care, 2010 Oct. PMID 20628086.
    4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

    See all (10) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
      Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
    2. Observational study of gene-disease association. (HuGE Navigator)
      Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:125852 BioGRID:113841 NCOA3    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Genotypes

    Homology

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    General protein information

    Preferred Names
    IQ domain-containing protein K
    Names
    IQ domain-containing protein K
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153208.1 → NP_694940.1  IQ domain-containing protein K

      Status: PROVISIONAL

      Source sequence(s)
      AF520570
      Consensus CDS
      CCDS10580.1
      UniProtKB/Swiss-Prot
      Q8N0W5
      Related
      ENSP00000324901, OTTHUMP00000162155, ENST00000320394, OTTHUMT00000254273

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000016.9 Reference GRCh37.p5 Primary Assembly

      Range
      19727778..19868861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000148.1 Alternate HuRef

      Range
      18264271..18405443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC002550.1 AAC05807.1
    genomic AC027130.5 (2098..33811) None
    genomic AC134300.3 (86100..167792) None
    genomic CH471186.1 EAW50295.1
      EAW50296.1
      EAW50297.1
      EAW50298.1
      EAW50299.1
      EAW50300.1
      EAW50301.1
    mRNA AF520569.1 AAM77339.1
    mRNA AF520570.1 AAM77340.1
    mRNA AK000122.1 None
    mRNA AK093894.1 BAG52781.1
    mRNA AK301933.1 BAG63353.1
    mRNA AK303998.1 BAG64915.1
    mRNA AK311216.1 None
    mRNA AK315672.1 BAG38037.1
    mRNA BC010515.1 AAH10515.1
    mRNA BC034823.1 AAH34823.1
    other-genetic GQ129337.1 ACT64471.1
    other-genetic GQ129338.1 ACT64472.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N0W5.1 GenPept UniProtKB/Swiss-Prot:Q8N0W5
    Q96FR4 GenPept UniProtKB/TrEMBL:Q96FR4
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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