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Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 [ Mus musculus (house mouse) ]

Gene ID: 12258, updated on 23-Aug-2016
Official Symbol
Serping1provided by MGI
Official Full Name
serine (or cysteine) peptidase inhibitor, clade G, member 1provided by MGI
Primary source
MGI:MGI:894696
See related
Ensembl:ENSMUSG00000023224 Vega:OTTMUSG00000013680
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C1nh; C1INH
Orthologs
Location:
2; 2 D
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (84765360..84775444, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (84605517..84615586, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene microRNA 130a Neighboring gene predicted gene, 19426 Neighboring gene predicted gene, 36596 Neighboring gene ubiquitin-conjugating enzyme E2L 6

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
complement binding IPI
Inferred from Physical Interaction
more info
PubMed 
peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
serine-type endopeptidase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
serine-type endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
blood coagulation IEA
Inferred from Electronic Annotation
more info
 
complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 
fibrinolysis IEA
Inferred from Electronic Annotation
more info
 
hemostasis IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of complement activation, lectin pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
blood microparticle ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
plasma protease C1 inhibitor
Names
C1 Inh
C1 esterase inhibitor
C1 inhibitor
C1-inhibiting factor
complement component 1 inhibitor
serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1
serine (or cysteine) proteinase inhibitor, clade G, member 1
serpin G1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009776.3NP_033906.2  plasma protease C1 inhibitor precursor

    See identical proteins and their annotated locations for NP_033906.2

    Status: VALIDATED

    Source sequence(s)
    AA237518, BQ031701, CA458230, Y10386
    Consensus CDS
    CCDS16193.1
    UniProtKB/Swiss-Prot
    P97290
    Related
    ENSMUSP00000023994, OTTMUSP00000014647, ENSMUST00000023994, OTTMUST00000032823
    Conserved Domains (1) summary
    cl00137
    Location:150499
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    84765360..84775444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498623.3XP_006498686.1  

    See identical proteins and their annotated locations for XP_006498686.1

    UniProtKB/Swiss-Prot
    P97290
    Conserved Domains (1) summary
    cl00137
    Location:150499
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...