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Bmx BMX non-receptor tyrosine kinase [ Mus musculus (house mouse) ]

Gene ID: 12169, updated on 8-May-2016
Official Symbol
Bmxprovided by MGI
Official Full Name
BMX non-receptor tyrosine kinaseprovided by MGI
Primary source
MGI:MGI:1101778
See related
Ensembl:ENSMUSG00000031377 Vega:OTTMUSG00000019502
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Etk; Tyro8; Etk/Bmx
Orthologs
Location:
X; X F
Exon count:
19
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (164192842..164258193, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (160630774..160696125, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 27 Neighboring gene angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Neighboring gene predicted gene, 19251 Neighboring gene pirin Neighboring gene c-fos induced growth factor Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class A

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
non-membrane spanning protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
NK T cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
peptidyl-tyrosine autophosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extrinsic component of cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
ruffle membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cytoplasmic tyrosine-protein kinase BMX
Names
TYRO8 protein tyrosine kinase 8
bone marrow tyrosine kinase gene in chromosome X protein homolog
NP_033889.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009759.4NP_033889.2  cytoplasmic tyrosine-protein kinase BMX

    Status: VALIDATED

    Source sequence(s)
    AK036707, AK040936
    Consensus CDS
    CCDS30519.2
    UniProtKB/Swiss-Prot
    P97504
    UniProtKB/TrEMBL
    B1AUL6
    Related
    ENSMUSP00000107884, OTTMUSP00000021030, ENSMUST00000112265, OTTMUST00000046571
    Conserved Domains (4) summary
    cd10399
    Location:269374
    SH2_Tec_Bmx; Src homology 2 (SH2) domain found in Tec protein, Bmx
    pfam07714
    Location:397646
    Pkinase_Tyr; Protein tyrosine kinase
    cd01238
    Location:25151
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
    cl21453
    Location:392647
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    164192842..164258193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    147407328..147474033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)