Display Settings:

Format

Send to:

Choose Destination

Bax BCL2-associated X protein [ Mus musculus (house mouse) ]

Gene ID: 12028, updated on 26-Oct-2014
Official Symbol
Baxprovided by MGI
Official Full Name
BCL2-associated X proteinprovided by MGI
Primary source
MGI:MGI:99702
See related
Ensembl:ENSMUSG00000003873
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Location:
7 B5; 7 29.32 cM
Exon count:
6
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 7 NC_000073.6 (45461695..45466899, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene RuvB-like protein 2 Neighboring gene glycogen synthase 1, muscle Neighboring gene ferritin light chain 1 Neighboring gene dihydrodiol dehydrogenase (dimeric) Neighboring gene tubby-like protein 2 Neighboring gene nucleobindin 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Activation, translocation and oligomerization of BAX, organism-specific biosystem (from REACTOME)
    Activation, translocation and oligomerization of BAX, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Amyotrophic lateral sclerosis (ALS), organism-specific biosystem (from KEGG)
    Amyotrophic lateral sclerosis (ALS), organism-specific biosystemAmyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons. The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord...
  • Amyotrophic lateral sclerosis (ALS), conserved biosystem (from KEGG)
    Amyotrophic lateral sclerosis (ALS), conserved biosystemAmyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons. The hallmark of this disease is the selective death of motor neurons in the brain and spinal cord...
  • Apoptosis, organism-specific biosystem (from WikiPathways)
    Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...
  • Apoptosis, organism-specific biosystem (from KEGG)
    Apoptosis, organism-specific biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis, conserved biosystem (from KEGG)
    Apoptosis, conserved biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
  • Apoptosis, organism-specific biosystem (from REACTOME)
    Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Apoptosis signaling pathway, organism-specific biosystem (from LIPID MAPS)
    Apoptosis signaling pathway, organism-specific biosystem
    Apoptosis signaling pathway
  • B Cell Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    B Cell Receptor Signaling Pathway, organism-specific biosystemThe B cell receptor includes membrane ???? heavy chain molecules bound to a light chain and an Ig alpha (CD79A)/Ig beta (CD79B) heterodimer. Activation of the B cell receptor involves phosphorylation...
  • Colorectal cancer, organism-specific biosystem (from KEGG)
    Colorectal cancer, organism-specific biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
  • Colorectal cancer, conserved biosystem (from KEGG)
    Colorectal cancer, conserved biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
  • HTLV-I infection, organism-specific biosystem (from KEGG)
    HTLV-I infection, organism-specific biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • HTLV-I infection, conserved biosystem (from KEGG)
    HTLV-I infection, conserved biosystemHuman T-lymphotropic virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammato...
  • Hepatitis B, organism-specific biosystem (from KEGG)
    Hepatitis B, organism-specific biosystemHepatitis B virus (HBV) is an enveloped virus and contains a partially double-stranded relaxed circular DNA (RC-DNA) genome. After entry into hepatocytes, HBV RC-DNA is transported to the nucleus and...
  • Huntington's disease, organism-specific biosystem (from KEGG)
    Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • Huntington's disease, conserved biosystem (from KEGG)
    Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • IL-3 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-3 Signaling Pathway, organism-specific biosystemInterleukin-3 belongs to a family of cytokines, which includes IL-5 and GM-CSF. It signals through a receptor complex comprising of an IL-3 specific IL-3 receptor alpha subunit (IL3RA) and a common b...
  • IL-5 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-5 Signaling Pathway, organism-specific biosystem
    IL-5 Signaling Pathway
  • IL-7 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    IL-7 Signaling Pathway, organism-specific biosystem
    IL-7 Signaling Pathway
  • Intrinsic Pathway for Apoptosis, organism-specific biosystem (from REACTOME)
    Intrinsic Pathway for Apoptosis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
  • Neurotrophin signaling pathway, organism-specific biosystem (from KEGG)
    Neurotrophin signaling pathway, organism-specific biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Neurotrophin signaling pathway, conserved biosystem (from KEGG)
    Neurotrophin signaling pathway, conserved biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Non-alcoholic fatty liver disease (NAFLD), organism-specific biosystem (from KEGG)
    Non-alcoholic fatty liver disease (NAFLD), organism-specific biosystemNon-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to more severe steatohepatitis with hepatic inflammation and fibrosis, known as nonalcoholic steatohepati...
  • Non-alcoholic fatty liver disease (NAFLD), conserved biosystem (from KEGG)
    Non-alcoholic fatty liver disease (NAFLD), conserved biosystemNon-alcoholic fatty liver disease (NAFLD) represents a spectrum ranging from simple steatosis to more severe steatohepatitis with hepatic inflammation and fibrosis, known as nonalcoholic steatohepati...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Prion diseases, organism-specific biosystem (from KEGG)
    Prion diseases, organism-specific biosystemPrion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of ...
  • Prion diseases, conserved biosystem (from KEGG)
    Prion diseases, conserved biosystemPrion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of ...
  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Viral carcinogenesis, organism-specific biosystem (from KEGG)
    Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Viral carcinogenesis, conserved biosystem (from KEGG)
    Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystem (from WikiPathways)
    XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystemXPodNet is a larger version of PodNet. Interactions from STRING database have been added to PodNet to build XPodNet. Hence, not all interactions found in XPodNet do necessarily have to be curated.
  • miRNA regulation of DNA Damage Response, organism-specific biosystem (from WikiPathways)
    miRNA regulation of DNA Damage Response, organism-specific biosystemThis is the first out of two pathways which deals with the DNA damage response. It is comprised of two central gene products (ATM and ATR) influenced by different sources of DNA damage (in blue). The...
  • p53 signaling pathway, organism-specific biosystem (from KEGG)
    p53 signaling pathway, organism-specific biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...
  • p53 signaling pathway, conserved biosystem (from KEGG)
    p53 signaling pathway, conserved biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
BH domain binding ISO
Inferred from Sequence Orthology
more info
 
BH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
channel activity ISO
Inferred from Sequence Orthology
more info
 
chaperone binding ISO
Inferred from Sequence Orthology
more info
 
heat shock protein binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
lipid binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein complex binding ISO
Inferred from Sequence Orthology
more info
 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
B cell apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
B cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
B cell homeostasis IGI
Inferred from Genetic Interaction
more info
PubMed 
B cell homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell homeostatic proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell negative selection IGI
Inferred from Genetic Interaction
more info
PubMed 
B cell receptor apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Sertoli cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
T cell homeostatic proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IDA
Inferred from Direct Assay
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c ISO
Inferred from Sequence Orthology
more info
 
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic mitochondrial changes IDA
Inferred from Direct Assay
more info
PubMed 
apoptotic mitochondrial changes ISO
Inferred from Sequence Orthology
more info
 
apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic process ISO
Inferred from Sequence Orthology
more info
 
apoptotic process involved in embryonic digit morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
apoptotic process involved in patterning of blood vessels IGI
Inferred from Genetic Interaction
more info
PubMed 
apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
blood vessel remodeling IGI
Inferred from Genetic Interaction
more info
PubMed 
cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular respiration ISO
Inferred from Sequence Orthology
more info
 
cellular response to DNA damage stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to UV IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular response to organic substance IDA
Inferred from Direct Assay
more info
PubMed 
cerebral cortex development IMP
Inferred from Mutant Phenotype
more info
PubMed 
development of secondary sexual characteristics IMP
Inferred from Mutant Phenotype
more info
PubMed 
ectopic germ cell programmed cell death IGI
Inferred from Genetic Interaction
more info
PubMed 
ectopic germ cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment or maintenance of transmembrane electrochemical gradient ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway in absence of ligand IGI
Inferred from Genetic Interaction
more info
PubMed 
extrinsic apoptotic signaling pathway via death domain receptors IDA
Inferred from Direct Assay
more info
PubMed 
fertilization IGI
Inferred from Genetic Interaction
more info
PubMed 
germ cell development IGI
Inferred from Genetic Interaction
more info
PubMed 
glycosphingolipid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
homeostasis of number of cells IGI
Inferred from Genetic Interaction
more info
PubMed 
homeostasis of number of cells IMP
Inferred from Mutant Phenotype
more info
PubMed 
homeostasis of number of cells within a tissue IMP
Inferred from Mutant Phenotype
more info
PubMed 
hypothalamus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
inner mitochondrial membrane organization ISO
Inferred from Sequence Orthology
more info
 
intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
intrinsic apoptotic signaling pathway by p53 class mediator IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage IGI
Inferred from Genetic Interaction
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IGI
Inferred from Genetic Interaction
more info
PubMed 
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
kidney development IGI
Inferred from Genetic Interaction
more info
PubMed 
leukocyte homeostasis IGI
Inferred from Genetic Interaction
more info
PubMed 
limb morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
male gonad development IGI
Inferred from Genetic Interaction
more info
PubMed 
male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrial fragmentation involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
mitochondrial fusion IGI
Inferred from Genetic Interaction
more info
PubMed 
mitochondrial fusion ISO
Inferred from Sequence Orthology
more info
 
mitochondrion morphogenesis IGI
Inferred from Genetic Interaction
more info
 
myeloid cell homeostasis IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of endoplasmic reticulum calcium ion concentration IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of fibroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of peptidyl-serine phosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
odontogenesis of dentin-containing tooth IGI
Inferred from Genetic Interaction
more info
PubMed 
outer mitochondrial membrane organization ISO
Inferred from Sequence Orthology
more info
 
ovarian follicle development IGI
Inferred from Genetic Interaction
more info
PubMed 
ovarian follicle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of B cell apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of apoptotic DNA fragmentation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process involved in mammary gland involution IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of calcium ion transport into cytosol IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of developmental pigmentation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of endoplasmic reticulum unfolded protein response ISO
Inferred from Sequence Orthology
more info
 
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of intrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of intrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitochondrial membrane permeability involved in apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein oligomerization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
positive regulation of release of sequestered calcium ion into cytosol IMP
Inferred from Mutant Phenotype
more info
PubMed 
post-embryonic camera-type eye morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
post-embryonic development IGI
Inferred from Genetic Interaction
more info
PubMed 
protein homooligomerization IDA
Inferred from Direct Assay
more info
PubMed 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein oligomerization ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
regulation of cell cycle IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mammary gland epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitochondrial membrane permeability involved in apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IMP
Inferred from Mutant Phenotype
more info
 
NOT regulation of mitochondrial membrane potential IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of nitrogen utilization IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
regulation of protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
release of cytochrome c from mitochondria IDA
Inferred from Direct Assay
more info
PubMed 
release of cytochrome c from mitochondria IGI
Inferred from Genetic Interaction
more info
PubMed 
release of cytochrome c from mitochondria ISO
Inferred from Sequence Orthology
more info
 
release of matrix enzymes from mitochondria ISO
Inferred from Sequence Orthology
more info
 
response to axon injury IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to gamma radiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to ionizing radiation IGI
Inferred from Genetic Interaction
more info
PubMed 
response to ionizing radiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to salt stress IGI
Inferred from Genetic Interaction
more info
PubMed 
response to toxic substance IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to toxic substance ISO
Inferred from Sequence Orthology
more info
 
response to wounding IMP
Inferred from Mutant Phenotype
more info
PubMed 
retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
retinal cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
retinal cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
sex differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
spermatid differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
spermatogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
thymocyte apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
transformed cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
vagina development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
BAX complex IPI
Inferred from Physical Interaction
more info
PubMed 
BAX complex ISO
Inferred from Sequence Orthology
more info
 
Bcl-2 family protein complex ISO
Inferred from Sequence Orthology
more info
 
cell IGI
Inferred from Genetic Interaction
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IGI
Inferred from Genetic Interaction
more info
PubMed 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
intracellular IGI
Inferred from Genetic Interaction
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial permeability transition pore complex ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IGI
Inferred from Genetic Interaction
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
pore complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
apoptosis regulator BAX
Names
apoptosis regulator BAX

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007527.3NP_031553.1  apoptosis regulator BAX

    See proteins identical to NP_031553.1

    Status: VALIDATED

    Source sequence(s)
    AK013298, AV355155, CJ078904
    Consensus CDS
    CCDS21246.1
    UniProtKB/Swiss-Prot
    Q07813
    UniProtKB/TrEMBL
    Q544Z6
    Related
    ENSMUSP00000033093, ENSMUST00000033093
    Conserved Domains (2) summary
    cd06845
    Location:25164
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    TIGR00865
    Location:5192
    bcl-2; apoptosis regulator

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000073.6 

    Range
    45461695..45466899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540584.1XP_006540647.1  

    Conserved Domains (2) summary
    cd06845
    Location:25159
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
    TIGR00865
    Location:5158
    bcl-2; apoptosis regulator

Alternate Mm_Celera

Genomic

  1. AC_000029.1 

    Range
    40917745..40922946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)