These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001162407.1 → NP_001155879.1 dual specificity protein kinase CLK1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site and upstream start codon, compared to variant 1. The resulting isoform (2) has a longer N-terminus, compared to isoform 1.
- Source sequence(s)
-
AI251890, AK294295
- Consensus CDS
-
CCDS54427.1
- Related
- ENSP00000394734, OTTHUMP00000206166, ENST00000434813, OTTHUMT00000336140
- Conserved Domains (2) summary
-
- smart00220
Location:203 – 519
Blast Score: 628
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl09925
Location:203 – 519
Blast Score: 434
- PKc_like; Protein Kinases, catalytic domain
-
NM_004071.3 → NP_004062.2 dual specificity protein kinase CLK1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the shorter isoform (1).
- Source sequence(s)
-
AI251890, BC031549, DA225472
- Consensus CDS
-
CCDS2331.1
- UniProtKB/Swiss-Prot
-
P49759
- Related
- ENSP00000326830, OTTHUMP00000163673, ENST00000321356, OTTHUMT00000256192
- Conserved Domains (2) summary
-
- smart00220
Location:161 – 477
Blast Score: 618
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl09925
Location:161 – 477
Blast Score: 430
- PKc_like; Protein Kinases, catalytic domain
RNA
-
NR_027855.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) lacks an alternate exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AI251890, BC028149, DA225472
-
NR_027856.1 RNA Sequence
- Description
- Transcript Variant: This variant (4) retains several introns, compared to variant 1. The transcript is sufficiently abundant to represent as a RefSeq record; however, the variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AI251890, BC028573, DA225472, DB164846
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000002.11 Reference GRCh37.p5 Primary Assembly
- Range
- 201717732..201729467, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000134.1 Alternate HuRef
- Range
- 193569145..193580882, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_001024646.1: Suppressed sequence
- Description
- NM_001024646.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.