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Atf3 activating transcription factor 3 [ Mus musculus (house mouse) ]

Gene ID: 11910, updated on 8-May-2016
Official Symbol
Atf3provided by MGI
Official Full Name
activating transcription factor 3provided by MGI
Primary source
MGI:MGI:109384
See related
Ensembl:ENSMUSG00000026628 Vega:OTTMUSG00000021405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LRG-21
Orthologs
Location:
1 H6; 1 96.28 cM
Exon count:
4
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (191170296..191183333, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (192994175..193007212, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31696 Neighboring gene family with sequence similarity 71, member A Neighboring gene RIKEN cDNA D730003I15 gene Neighboring gene predicted gene, 37168

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cellular response to amino acid starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
PubMed 
gluconeogenesis IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of ERK1 and ERK2 cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of TRAIL-activated apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
CHOP-ATF3 complex ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cyclic AMP-dependent transcription factor ATF-3
Names
cAMP-dependent transcription factor ATF-3
transcription factor LRG-21

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007498.3NP_031524.2  cyclic AMP-dependent transcription factor ATF-3

    See identical proteins and their annotated locations for NP_031524.2

    Status: VALIDATED

    Source sequence(s)
    AK133965, BE199676
    Consensus CDS
    CCDS15616.1
    UniProtKB/Swiss-Prot
    Q60765
    UniProtKB/TrEMBL
    Q4FJW1
    Related
    ENSMUSP00000027941, OTTMUSP00000023761, ENSMUST00000027941, OTTMUST00000050734
    Conserved Domains (1) summary
    cd14722
    Location:96149
    bZIP_ATF3; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-3 (ATF-3) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    191170296..191183333 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    198095832..198108890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)