These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_027845.1 RefSeqGene
- Range
- 5000..22894
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001831.3 → NP_001822.3 clusterin preproprotein
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the functional protein.
- Source sequence(s)
-
AF311103, BC010514, BM682289, DN990822
- Consensus CDS
-
CCDS47832.1
- UniProtKB/Swiss-Prot
-
P10909
- Conserved Domains (3) summary
-
- smart00030
Location:23 – 227
Blast Score: 874
- CLb; CLUSTERIN Beta chain
- smart00035
Location:228 – 443
Blast Score: 1016
- CLa; CLUSTERIN alpha chain
- pfam01093
Location:29 – 449
Blast Score: 1568
- Clusterin; Clusterin
RNA
-
NR_038335.1 RNA Sequence
- Description
- Transcript Variant: This variant (3) has an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AF311103, BM682289, M25915
-
NR_045494.1 RNA Sequence
- Description
- Transcript Variant: This variant (4) has an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AF311103, BC019588, BM682289, BP193735, EB385800
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000008.10 Reference GRCh37.p5 Primary Assembly
- Range
- 27454434..27472328, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000140.1 Alternate HuRef
- Range
- 25999468..26017387, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)