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    Ass1 argininosuccinate synthetase 1 [ Mus musculus ]

    Gene ID: 11898, updated on 19-Feb-2012

    Summary

    Official Symbol
    Ass1provided by MGI
    Official Full Name
    argininosuccinate synthetase 1provided by MGI
    Primary source
    MGI:88090
    Locus tag
    RP23-442G9.2
    See related
    Ensembl:ENSMUSG00000076441; Vega:OTTMUSG00000012079
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ASS; fold; Ass-1; AA408052

    Genomic context

    Location :
    2 B; 2 20.0 cM
    Sequence :
    Chromosome: 2; NC_000068.6 (31325790..31376190)
    See Ass1 in Epigenomics, MapViewer

    Chromosome 2 - NC_000068.6Genomic Context describing neighboring genes Neighboring gene neuronal calcium sensor 1 Neighboring gene hemicentin 2 Neighboring gene ribosomal protein SA pseudogene Neighboring gene far upstream element (FUSE) binding protein 3

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    • Homologs of the Ass1 gene: The Ass1 gene is conserved in human, chimpanzee, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, and rice.
    • Map Viewer (Human, Rat)

    Pathways from BioSystems

    Clone Names

    • MGC103151

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    argininosuccinate synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    toxin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    arginine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    argininosuccinate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    cellular amino acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    response to biotic stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    response to glucocorticoid stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    response to zinc ion ISO
    Inferred from Sequence Orthology
    more info
     
    urea cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell body fiber ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perikaryon ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    argininosuccinate synthase
    Names
    argininosuccinate synthase
    arginosuccinate synthetase 1
    citrulline--aspartate ligase
    NP_031520.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007494.3NP_031520.1  argininosuccinate synthase

      Status: PROVISIONAL

      Source sequence(s)
      AL732564
      Consensus CDS
      CCDS15898.1
      UniProtKB/Swiss-Prot
      P16460
      UniProtKB/TrEMBL
      Q3UJ34
      Related
      ENSMUSP00000099904, OTTMUSP00000013008, ENSMUST00000102840, OTTMUST00000028752
      Conserved Domains (2) summary
      cd01999
      Location:7398
      Blast Score: 1455
      Argininosuccinate_Synthase; Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In ...
      COG0137
      Location:1408
      Blast Score: 1305
      ArgG; Argininosuccinate synthase [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: Build 37.2

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MGSCv37 C57BL/6J

    Genomic

    1. NC_000068.6 Reference MGSCv37 C57BL/6J

      Range
      31325790..31376190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000024.1 Alternate Mm_Celera

      Range
      31171177..31221646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AL732564.12 CAM24505.1
    genomic CH466542.1 EDL08509.1 mixed
    genomic HB892460.1 CBF71294.1
    genomic HB898722.1 CBF77513.1
    genomic HB902515.1 CBF81489.1
    genomic HB948472.1 CBG08939.1
    genomic HB956534.1 CBG12891.1
    genomic HC949869.1 CBU95142.1
    genomic HC956131.1 CBU98143.1
    genomic HC959924.1 CBU99973.1
    genomic HD005882.1 CBV22461.1
    genomic HD013944.1 CBV26405.1
    genomic M31691.1 None BALB/c
    genomic M31692.1 AAB60707.1 BALB/c
    genomic M31693.1 AAB60708.1 BALB/c
    genomic M31694.1 AAB60708.1 BALB/c
    genomic M31695.1 AAB60708.1 BALB/c
    genomic M31696.1 None BALB/c
    genomic M31697.1 AAB60706.1 BALB/c
    genomic M31698.1 AAB60706.1 BALB/c
    genomic M31699.1 AAB60706.1 BALB/c
    genomic M31700.1 AAB60706.1 BALB/c
    genomic M31701.1 AAB60706.1 BALB/c
    genomic M31702.1 AAB60706.1
    genomic M31703.1 AAB60706.1 BALB/c
    mRNA AK146635.1 BAE27321.1 C57BL/6J
    mRNA AK149489.1 BAE28914.1 C57BL/6J
    mRNA BC002074.1 AAH02074.1 CZECHII
    mRNA BC087556.1 AAH87556.1 FVB/N
    mRNA M31690.1 AAA37266.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    P16460.1 GenPept UniProtKB/Swiss-Prot:P16460
    Q3UEJ7 GenPept UniProtKB/TrEMBL:Q3UEJ7
    Q3UJ34 GenPept UniProtKB/TrEMBL:Q3UJ34

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