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Arnt2 aryl hydrocarbon receptor nuclear translocator 2 [ Mus musculus (house mouse) ]

Gene ID: 11864, updated on 8-May-2016
Official Symbol
Arnt2provided by MGI
Official Full Name
aryl hydrocarbon receptor nuclear translocator 2provided by MGI
Primary source
MGI:MGI:107188
See related
Ensembl:ENSMUSG00000015709 Vega:OTTMUSG00000059598
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hif-2b; bHLHe1; mKIAA0307
Orthologs
Location:
7 D3; 7 48.35 cM
Exon count:
22
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (84246274..84410171, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (91394788..91510183, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 17C Neighboring gene predicted gene, 26708 Neighboring gene predicted gene, 39044 Neighboring gene predicted gene, 30873 Neighboring gene predicted gene, 39045 Neighboring gene predicted gene, 31284

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
brain development ISO
Inferred from Sequence Orthology
more info
 
central nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated ISA
Inferred from Sequence Alignment
more info
PubMed 
response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
response to hypoxia TAS
Traceable Author Statement
more info
PubMed 
response to toxic substance TAS
Traceable Author Statement
more info
PubMed 
response to xenobiotic stimulus TAS
Traceable Author Statement
more info
PubMed 
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
transcription factor complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
aryl hydrocarbon receptor nuclear translocator 2
Names
ARNT protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007488.3NP_031514.3  aryl hydrocarbon receptor nuclear translocator 2

    See identical proteins and their annotated locations for NP_031514.3

    Status: VALIDATED

    Source sequence(s)
    BC054546, BM115235, BU056629, D63644
    Consensus CDS
    CCDS59733.1
    UniProtKB/Swiss-Prot
    Q61324
    Related
    ENSMUSP00000082154, OTTMUSP00000076134, ENSMUST00000085077, OTTMUST00000146143
    Conserved Domains (4) summary
    cd00083
    Location:65117
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:336432
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:137243
    PAS; PAS fold
    pfam14598
    Location:336436
    PAS_11; PAS domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    84246274..84410171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507239.2XP_006507302.1  

    Conserved Domains (4) summary
    cd00083
    Location:62113
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:332428
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:133239
    PAS; PAS fold
    pfam14598
    Location:332432
    PAS_11; PAS domain
  2. XM_006507244.2XP_006507307.1  

    Conserved Domains (4) summary
    cd00083
    Location:65117
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:336432
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:137243
    PAS; PAS fold
    pfam14598
    Location:336436
    PAS_11; PAS domain
  3. XM_006507242.1XP_006507305.1  

    See identical proteins and their annotated locations for XP_006507305.1

    UniProtKB/Swiss-Prot
    Q61324
    Related
    ENSMUSP00000147129, OTTMUSP00000076135, ENSMUST00000209133, OTTMUST00000146144
    Conserved Domains (4) summary
    cd00083
    Location:54106
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:325421
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:126232
    PAS; PAS fold
    pfam14598
    Location:325425
    PAS_11; PAS domain
  4. XM_011241655.1XP_011239957.1  

    See identical proteins and their annotated locations for XP_011239957.1

    UniProtKB/Swiss-Prot
    Q61324
    Conserved Domains (4) summary
    cd00083
    Location:54106
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:325421
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:126232
    PAS; PAS fold
    pfam14598
    Location:325425
    PAS_11; PAS domain
  5. XM_006507240.1XP_006507303.1  

    See identical proteins and their annotated locations for XP_006507303.1

    UniProtKB/Swiss-Prot
    Q61324
    Related
    ENSMUSP00000146413, OTTMUSP00000076136, ENSMUST00000208232, OTTMUST00000146145
    Conserved Domains (4) summary
    cd00083
    Location:54106
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:325421
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:126232
    PAS; PAS fold
    pfam14598
    Location:325425
    PAS_11; PAS domain
  6. XM_006507243.1XP_006507306.1  

    Conserved Domains (4) summary
    cd00083
    Location:51102
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:321417
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:122228
    PAS; PAS fold
    pfam14598
    Location:321421
    PAS_11; PAS domain
  7. XM_006507238.2XP_006507301.1  

    Conserved Domains (4) summary
    cd00083
    Location:65117
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:336432
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:137243
    PAS; PAS fold
    pfam14598
    Location:336436
    PAS_11; PAS domain

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    81653321..81815277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)