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Aqp3 aquaporin 3 [ Mus musculus (house mouse) ]

Gene ID: 11828, updated on 8-May-2016
Official Symbol
Aqp3provided by MGI
Official Full Name
aquaporin 3provided by MGI
Primary source
MGI:MGI:1333777
See related
Ensembl:ENSMUSG00000028435 Vega:OTTMUSG00000006621
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AQP-2
Orthologs
Location:
4; 4 B1
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (41092724..41098183, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (41039757..41045216, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene nuclear transcription factor, X-box binding 1 Neighboring gene microRNA 3094 Neighboring gene aquaporin 7 Neighboring gene nucleolar protein family 6 (RNA-associated) Neighboring gene ubiquitin-conjugating enzyme E2R 2 Neighboring gene predicted gene 12403

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Chemically induced (ENU) (1) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
glycerol channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
glycerol channel activity ISO
Inferred from Sequence Orthology
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
urea transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
water channel activity ISO
Inferred from Sequence Orthology
more info
 
water channel activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
carbohydrate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular water homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
glycerol transport IDA
Inferred from Direct Assay
more info
PubMed 
ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of immune system process ISO
Inferred from Sequence Orthology
more info
 
renal water absorption IGI
Inferred from Genetic Interaction
more info
PubMed 
renal water absorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
urea transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
urea transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
water transport IDA
Inferred from Direct Assay
more info
PubMed 
water transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
water transport ISO
Inferred from Sequence Orthology
more info
 
water transport TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
aquaporin-3
Names
AQP-3
aquaglyceroporin-3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016689.2NP_057898.2  aquaporin-3

    See identical proteins and their annotated locations for NP_057898.2

    Status: VALIDATED

    Source sequence(s)
    AK145678
    Consensus CDS
    CCDS38714.1
    UniProtKB/Swiss-Prot
    Q8R2N1
    Related
    ENSMUSP00000055110, OTTMUSP00000006982, ENSMUST00000055327, OTTMUST00000015099
    Conserved Domains (1) summary
    cd00333
    Location:23264
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    41092724..41098183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    40753580..40759039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)