Format

Send to:

Choose Destination

Apoc2 apolipoprotein C-II [ Mus musculus (house mouse) ]

Gene ID: 11813, updated on 21-May-2016
Official Symbol
Apoc2provided by MGI
Official Full Name
apolipoprotein C-IIprovided by MGI
Primary source
MGI:MGI:88054
See related
Ensembl:ENSMUSG00000002992 Ensembl:ENSMUSG00000109350 Vega:OTTMUSG00000032974
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
apo-CII; apoC-II
Orthologs
Location:
7 A3; 7 9.94 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (19671579..19677941, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (20256928..20262213, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene avian reticuloendotheliosis viral (v-rel) oncogene related B Neighboring gene cleft lip and palate associated transmembrane protein 1 Neighboring gene apolipoprotein C-IV Neighboring gene apolipoprotein C-I

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Readthrough Apoc4-apoc2

Readthrough gene: Apoc4-apoc2, Included gene: Apoc4

Homology

Clone Names

  • MGC117889

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 
lipase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
lipid binding ISO
Inferred from Sequence Orthology
more info
 
lipoprotein lipase activator activity ISO
Inferred from Sequence Orthology
more info
 
phospholipase activator activity ISO
Inferred from Sequence Orthology
more info
 
phospholipase binding ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cholesterol efflux ISO
Inferred from Sequence Orthology
more info
 
chylomicron remnant clearance ISO
Inferred from Sequence Orthology
more info
 
high-density lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
 
lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid transport IEA
Inferred from Electronic Annotation
more info
 
lipoprotein transport ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
negative regulation of lipid metabolic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of very-low-density lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
 
phospholipid efflux ISO
Inferred from Sequence Orthology
more info
 
positive regulation of fatty acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lipoprotein lipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phospholipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phospholipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of triglyceride catabolic process ISO
Inferred from Sequence Orthology
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
triglyceride homeostasis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
chylomicron ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
high-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 
intermediate-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
low-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
spherical high-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
very-low-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
apolipoprotein C-II
Names
apolipoprotein C2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277944.1NP_001264873.1  apolipoprotein C-II precursor

    See identical proteins and their annotated locations for NP_001264873.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC149282, BG085960
    Consensus CDS
    CCDS39801.1
    UniProtKB/Swiss-Prot
    Q05020
    UniProtKB/TrEMBL
    Q3UJG0
    Related
    ENSMUSP00000115173, OTTMUSP00000044049, ENSMUST00000142352, OTTMUST00000082221
    Conserved Domains (1) summary
    pfam05355
    Location:2197
    Apo-CII; Apolipoprotein C-II
  2. NM_001309795.1NP_001296724.1  apolipoprotein C-II precursor

    See identical proteins and their annotated locations for NP_001296724.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA059961, AC149282, AK146468
    UniProtKB/Swiss-Prot
    Q05020
    UniProtKB/TrEMBL
    Q3UJG0
    Conserved Domains (1) summary
    pfam05355
    Location:2197
    Apo-CII; Apolipoprotein C-II

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    19671579..19677941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    17077835..17084024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)